Concepts of Genetics (12th Edition)

12th Edition

ISBN: 9780134604718

Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian

Publisher: PEARSON

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Concept explainers

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of anoth…

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.

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Textbook Question

Chapter 18, Problem 12PDQ

Present an overview of RNA interference (RNAi). How does the silencing process begin, and what major components participate?

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Chapter 18, Problem 11PDQ

Chapter 18, Problem 13PDQ

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Chapter 18 Solutions

Concepts of Genetics (12th Edition)

Ch. 18 - Some mutations in the tra gene of Drosophila cause...Ch. 18 - Some scientists use the analogy that the...Ch. 18 - Consider the example that actin mRNA localization...Ch. 18 - What is alternative splicing, where does it occur,...Ch. 18 - What role might the expanded tri- and...Ch. 18 - DM1 is characterized by a phenomenon known as...Ch. 18 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 18 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 18 - List three types of alternative splicing patterns...Ch. 18 - Consider the CT/CGRP example of alternative...

Ch. 18 - Explain how the use of alternative promoters and...Ch. 18 - Explain how a tissue-specific RNA-binding protein...Ch. 18 - The regulation of mRNA decay relies heavily upon...Ch. 18 - Nonsense-mediated decay is an mRNA surveillance...Ch. 18 - AU-rich elements (AREs) are cis-elements in mRNAs...Ch. 18 - What are processing bodies (P bodies), and what...Ch. 18 - In 1998, future Nobel laureates Andrew Fire and...Ch. 18 - Present an overview of RNA interference (RNAi)....Ch. 18 - RNAi may be directed by small interfering RNAs...Ch. 18 - Prob. 14PDQ Ch. 18 - In principle, RNAi may be used to fight viral...Ch. 18 - Prob. 16PDQ Ch. 18 - Prob. 17PDQ Ch. 18 - Prob. 18PDQ Ch. 18 - Prob. 19PDQ Ch. 18 - How is it possible that a given mRNA in a cell is...Ch. 18 - Prob. 21PDQ Ch. 18 - Prob. 22PDQ Ch. 18 - Prob. 23PDQ Ch. 18 - Prob. 24ESP Ch. 18 - Prob. 25ESP Ch. 18 - Mutations in the low-density lipoprotein receptor...Ch. 18 - RNA helicases are a class of proteins that bind...Ch. 18 - While miRNA response elements (MREs) may be...Ch. 18 - RNAi is currently being tested as a therapeutic...Ch. 18 - The localization and translational control of...Ch. 18 - Explain how the expression of a single gene can be...

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