Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 18, Problem 5PDQ
Explain how the use of alternative promoters and alternative polyadenylation signals produces mRNAs with different 5′ and 3′ ends.
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Chapter 18 Solutions
Concepts of Genetics (12th Edition)
Ch. 18 - Some mutations in the tra gene of Drosophila cause...Ch. 18 - Some scientists use the analogy that the...Ch. 18 - Consider the example that actin mRNA localization...Ch. 18 - What is alternative splicing, where does it occur,...Ch. 18 - What role might the expanded tri- and...Ch. 18 - DM1 is characterized by a phenomenon known as...Ch. 18 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 18 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 18 - List three types of alternative splicing patterns...Ch. 18 - Consider the CT/CGRP example of alternative...
Ch. 18 - Explain how the use of alternative promoters and...Ch. 18 - Explain how a tissue-specific RNA-binding protein...Ch. 18 - The regulation of mRNA decay relies heavily upon...Ch. 18 - Nonsense-mediated decay is an mRNA surveillance...Ch. 18 - AU-rich elements (AREs) are cis-elements in mRNAs...Ch. 18 - What are processing bodies (P bodies), and what...Ch. 18 - In 1998, future Nobel laureates Andrew Fire and...Ch. 18 - Present an overview of RNA interference (RNAi)....Ch. 18 - RNAi may be directed by small interfering RNAs...Ch. 18 - Prob. 14PDQCh. 18 - In principle, RNAi may be used to fight viral...Ch. 18 - Prob. 16PDQCh. 18 - Prob. 17PDQCh. 18 - Prob. 18PDQCh. 18 - Prob. 19PDQCh. 18 - How is it possible that a given mRNA in a cell is...Ch. 18 - Prob. 21PDQCh. 18 - Prob. 22PDQCh. 18 - Prob. 23PDQCh. 18 - Prob. 24ESPCh. 18 - Prob. 25ESPCh. 18 - Mutations in the low-density lipoprotein receptor...Ch. 18 - RNA helicases are a class of proteins that bind...Ch. 18 - While miRNA response elements (MREs) may be...Ch. 18 - RNAi is currently being tested as a therapeutic...Ch. 18 - The localization and translational control of...Ch. 18 - Explain how the expression of a single gene can be...
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- Give an account of post transcriptional modification of a eukaryotic Mrna?arrow_forwardDefine regulatory mutation. Describe how an insertion, deletion, or substituion of a base pair in a promoter might affect the transcription driven by that promoter.arrow_forwardDescribe what happens when a nonsense mutation is introduced into the gene encoding transposase within a transposon.arrow_forward
- Describe why base substitutions that differ from the consensus sequence of a core promoter may alter gene expression. Will expression go up or down?arrow_forwardDescribe in discrete steps how a polyadenylation signal contributes to the formation of a mature mRNA with a poly A tail of more than 300 nucleotides longarrow_forwardWith examples explain the importance of Non-coding ribonucleic acid interference in regards to gene expression?arrow_forward
- Does RNA Polymerase II terminate transcription at the polyadenylation signal? Describe in discrete steps how a polyadenylation signal contributes to the formation of a mature mRNA with a poly A tail of more than 300 nucleotides long How does this poly A tail affect the mature mRNA?arrow_forwardDescribe the connection between silent mutations and redundancy of the code. arrow_forwardExplain three types of post-transcriptional modifications to RNA.arrow_forward
- Explain how degeneracy of the genetic code makes cells better able to accomodate mutations.arrow_forwardDiscuss how degeneracy of the genetic code makes cells more robust to mutations.arrow_forwardExplain how the pausing of the ribosome in the presence or absence of tryptophan affects the formation of a terminator (3–4) stem-loop, and describe how this affects transcription.arrow_forward
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