The reagents and conditions that are required for the given transformation have to be determined. Concept Introduction: Acetals: Acetals are used to protect the ketone and aldehyde (carbonyl group). In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound. In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively. General scheme: Retro synthetic analysis: It is the analysis of the synthetic starting materials for a given compound through its precursors or fragments which are known as synthons. The synthons can be obtained by logical cleavage of the chemical bonds in the compounds. The resulted synthons will be therefore known as logical synthons. Retro analysis for acetal formation: The retro synthetic analysis for any given acetal, enable to find that the starting materials for its formation will be alcohol in case of aliphatic acetal or diol in case of cyclic acetal as well as aldehyde or ketone. Example: The retro analysis for a cyclic acetal is shown here: The given retro analysis shows that the starting materials for the formation of the acetal are a diol and formaldehyde. General scheme:

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Answer 1

Question

Chapter 19.5, Problem 9ATS

(a)

Interpretation Introduction

Interpretation: The reagents and conditions that are required for the given transformation have to be determined.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Retro synthetic analysis:

It is the analysis of the synthetic starting materials for a given compound through its precursors or fragments which are known as synthons. The synthons can be obtained by logical cleavage of the chemical bonds in the compounds. The resulted synthons will be therefore known as logical synthons.

Retro analysis for acetal formation:

The retro synthetic analysis for any given acetal, enable to find that the starting materials for its formation will be alcohol in case of aliphatic acetal or diol in case of cyclic acetal as well as aldehyde or ketone.

Example:

The retro analysis for a cyclic acetal is shown here:

The given retro analysis shows that the starting materials for the formation of the acetal are a diol and formaldehyde.

General scheme:

(b)

Interpretation Introduction

Interpretation: A plausible mechanism for the given reaction has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

(c)

Interpretation Introduction

Interpretation: Based on the given keto-diol precursor, the structure of frontalin has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

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Answer 2

Question

Chapter 19.5, Problem 9ATS

(a)

Interpretation Introduction

Interpretation: The reagents and conditions that are required for the given transformation have to be determined.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Retro synthetic analysis:

It is the analysis of the synthetic starting materials for a given compound through its precursors or fragments which are known as synthons. The synthons can be obtained by logical cleavage of the chemical bonds in the compounds. The resulted synthons will be therefore known as logical synthons.

Retro analysis for acetal formation:

The retro synthetic analysis for any given acetal, enable to find that the starting materials for its formation will be alcohol in case of aliphatic acetal or diol in case of cyclic acetal as well as aldehyde or ketone.

Example:

The retro analysis for a cyclic acetal is shown here:

The given retro analysis shows that the starting materials for the formation of the acetal are a diol and formaldehyde.

General scheme:

(b)

Interpretation Introduction

Interpretation: A plausible mechanism for the given reaction has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

(c)

Interpretation Introduction

Interpretation: Based on the given keto-diol precursor, the structure of frontalin has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

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Answer 3

Question

Chapter 19.5, Problem 9ATS

(a)

Interpretation Introduction

Interpretation: The reagents and conditions that are required for the given transformation have to be determined.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Retro synthetic analysis:

It is the analysis of the synthetic starting materials for a given compound through its precursors or fragments which are known as synthons. The synthons can be obtained by logical cleavage of the chemical bonds in the compounds. The resulted synthons will be therefore known as logical synthons.

Retro analysis for acetal formation:

The retro synthetic analysis for any given acetal, enable to find that the starting materials for its formation will be alcohol in case of aliphatic acetal or diol in case of cyclic acetal as well as aldehyde or ketone.

Example:

The retro analysis for a cyclic acetal is shown here:

The given retro analysis shows that the starting materials for the formation of the acetal are a diol and formaldehyde.

General scheme:

(b)

Interpretation Introduction

Interpretation: A plausible mechanism for the given reaction has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

(c)

Interpretation Introduction

Interpretation: Based on the given keto-diol precursor, the structure of frontalin has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

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Answer 4

Question

Chapter 19.5, Problem 9ATS

(a)

Interpretation Introduction

Interpretation: The reagents and conditions that are required for the given transformation have to be determined.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Retro synthetic analysis:

It is the analysis of the synthetic starting materials for a given compound through its precursors or fragments which are known as synthons. The synthons can be obtained by logical cleavage of the chemical bonds in the compounds. The resulted synthons will be therefore known as logical synthons.

Retro analysis for acetal formation:

The retro synthetic analysis for any given acetal, enable to find that the starting materials for its formation will be alcohol in case of aliphatic acetal or diol in case of cyclic acetal as well as aldehyde or ketone.

Example:

The retro analysis for a cyclic acetal is shown here:

The given retro analysis shows that the starting materials for the formation of the acetal are a diol and formaldehyde.

General scheme:

(b)

Interpretation Introduction

Interpretation: A plausible mechanism for the given reaction has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

(c)

Interpretation Introduction

Interpretation: Based on the given keto-diol precursor, the structure of frontalin has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

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Answer 5

Chapter 19.5, Problem 9ATS

(a)

Interpretation Introduction

Interpretation: The reagents and conditions that are required for the given transformation have to be determined.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Retro synthetic analysis:

It is the analysis of the synthetic starting materials for a given compound through its precursors or fragments which are known as synthons. The synthons can be obtained by logical cleavage of the chemical bonds in the compounds. The resulted synthons will be therefore known as logical synthons.

Retro analysis for acetal formation:

The retro synthetic analysis for any given acetal, enable to find that the starting materials for its formation will be alcohol in case of aliphatic acetal or diol in case of cyclic acetal as well as aldehyde or ketone.

Example:

The retro analysis for a cyclic acetal is shown here:

The given retro analysis shows that the starting materials for the formation of the acetal are a diol and formaldehyde.

General scheme:

(b)

Interpretation Introduction

Interpretation: A plausible mechanism for the given reaction has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

(c)

Interpretation Introduction

Interpretation: Based on the given keto-diol precursor, the structure of frontalin has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Answer 6

Chapter 19.5, Problem 9ATS

(a)

Interpretation Introduction

Interpretation: The reagents and conditions that are required for the given transformation have to be determined.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Retro synthetic analysis:

It is the analysis of the synthetic starting materials for a given compound through its precursors or fragments which are known as synthons. The synthons can be obtained by logical cleavage of the chemical bonds in the compounds. The resulted synthons will be therefore known as logical synthons.

Retro analysis for acetal formation:

The retro synthetic analysis for any given acetal, enable to find that the starting materials for its formation will be alcohol in case of aliphatic acetal or diol in case of cyclic acetal as well as aldehyde or ketone.

Example:

The retro analysis for a cyclic acetal is shown here:

The given retro analysis shows that the starting materials for the formation of the acetal are a diol and formaldehyde.

General scheme:

Answer 7

Chapter 19.5, Problem 9ATS

(a)

Interpretation Introduction

Interpretation: The reagents and conditions that are required for the given transformation have to be determined.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Retro synthetic analysis:

It is the analysis of the synthetic starting materials for a given compound through its precursors or fragments which are known as synthons. The synthons can be obtained by logical cleavage of the chemical bonds in the compounds. The resulted synthons will be therefore known as logical synthons.

Retro analysis for acetal formation:

The retro synthetic analysis for any given acetal, enable to find that the starting materials for its formation will be alcohol in case of aliphatic acetal or diol in case of cyclic acetal as well as aldehyde or ketone.

Example:

The retro analysis for a cyclic acetal is shown here:

The given retro analysis shows that the starting materials for the formation of the acetal are a diol and formaldehyde.

General scheme:

Answer 8

(b)

Interpretation Introduction

Interpretation: A plausible mechanism for the given reaction has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Answer 9

(b)

Interpretation Introduction

Interpretation: A plausible mechanism for the given reaction has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Answer 10

(c)

Interpretation Introduction

Interpretation: Based on the given keto-diol precursor, the structure of frontalin has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Answer 11

(c)

Interpretation Introduction

Interpretation: Based on the given keto-diol precursor, the structure of frontalin has to be drawn.

Concept Introduction:

Acetals:

Acetals are used to protect the ketone and aldehyde (carbonyl group).

In this reaction acetone is protected as acetal by using ethylene glycol. Acetals are less stable compound.

In acidic condition, an aldehyde or a ketone reacts with two molecules of alcohol or a molecule of diol to form acetal or cyclic acetal respectively.

General scheme:

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 19.2 - Prob. 1LTS Ch. 19.2 - Prob. 1PTS Ch. 19.2 - Prob. 2PTS Ch. 19.2 - APPLY the skill Compounds with two ketone groups...Ch. 19.2 - Prob. 4ATS Ch. 19.3 - Prob. 5CC Ch. 19.4 - Prob. 6CC Ch. 19.5 - Prob. 7CC Ch. 19.5 - Prob. 2LTS Ch. 19.5 - Prob. 8PTS

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