Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 3, Problem 29P
In mice, the AY allele of the agouti gene is a recessive lethal allele, but it is dominant for yellow coat color. What
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Miniature wings (Xm) in Drosophila result from an X-linked allele that is recessive to
the allele for long wings (X*). Give the genotypes of the parents in the following
cross:
Male parent
Female parent
Male offspring
Female offspring
Long
Miniature
750 miniature
761 long
O male: X* / X* and female X™ /x+
O male: X*/Xt and female Xm /xm
O male: X*/ Y and female Xm /xm
O male: Xm/ Y and female Xm /xm
In Drosophila fruit flies, the genes for warped wings (dwp), rumpled bristles (rmp), and pallid wings (pld) are linked. A trihybrid female for all three allleles is crossed with homozygous recessive male for all three alleles and the offspring obtained showed the following phenotypes:
3 pld rmp dwp
428 pld rmp +
427 + + dwp
48 + rmp +
47 pld + dwp
23 pld + +
2 + + +
22 + rmp dwp
What is the order and map distance between these three alleles?
In Drosophila, the sepia mutation (se, chromosome 3, position 26) results in dark brown eyes, while cinnabar (cn, chromosome 2, position 57.5) results in bright orange-red eyes. True breeding, wild type females are mated with true breeding males homozygous recessive for both traits.
Using Drosophila notation, diagram the P1 and F1 crosses.
P1 F1
Fill in the chart with phenotypic ratios that would be expected in the F2 generation. Use the space provided to show your work.
Phenotype
Females
Males
Overall (♀and ♂)
=1 =1
Chapter 3 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 3 - For each of the terms in the left column, choose...Ch. 3 - In four-oclocks, the allele for red flowers is...Ch. 3 - The Aa heterozygous snapdragons in Fig. 3.3 are...Ch. 3 - In the fruit fly Drosophila melanogaster, very...Ch. 3 - A cross between two plants that both have yellow...Ch. 3 - In radishes, color and shape are each controlled...Ch. 3 - A wild legume with white flowers and long pods is...Ch. 3 - Prob. 8PCh. 3 - Assuming no involvement of the Bombay phenotype:...Ch. 3 - Several genes in humans in addition to the ABO...
Ch. 3 - Alleles of the gene that determines seed coat...Ch. 3 - Prob. 12PCh. 3 - In a population of rabbits, you find three...Ch. 3 - In clover plants, the pattern on the leaves is...Ch. 3 - Fruit flies with one allele for curly wings Cy and...Ch. 3 - Prob. 16PCh. 3 - In a species of tropical fish, a colorful orange...Ch. 3 - A rooster with a particular comb morphology called...Ch. 3 - A black mare was crossed to a chestnut stallion...Ch. 3 - Prob. 20PCh. 3 - Prob. 21PCh. 3 - a. How could you describe inheritance of flower...Ch. 3 - Explain the difference between epistasis and...Ch. 3 - The dominant allele H reduces the number of body...Ch. 3 - Secretors genotypes SS and Ss secrete their A and...Ch. 3 - Normally, wild violets have yellow petals with...Ch. 3 - Prob. 27PCh. 3 - Three different pure-breeding strains of corn that...Ch. 3 - In mice, the AY allele of the agouti gene is a...Ch. 3 - A student whose hobby was fishing pulled a very...Ch. 3 - Prob. 31PCh. 3 - Prob. 32PCh. 3 - Three genes in fruit flies affect a particular...Ch. 3 - The garden flower Salpiglossis sinuata painted...Ch. 3 - In foxgloves, there are three different petal...Ch. 3 - In a culture of fruit flies, matings between any...Ch. 3 - Suppose that blue flower color in a plant species...Ch. 3 - Prob. 38PCh. 3 - Considering your answers to Problem 38, does the...Ch. 3 - Prob. 40PCh. 3 - Prob. 41PCh. 3 - Familial hypercholesterolemia FH is an inherited...Ch. 3 - You have come into contact with two unrelated...Ch. 3 - Polycystic kidney disease is a dominant trait that...Ch. 3 - Using each of the seven coat color genes discussed...
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- Miniature wings (Xm) in Drosophila result from an X-linked allele that is recessive to the allele for long wings (X*). Give the genotypes of the parents in the following cross: Male parent Female parent Male offspring Female offspring 231 long, 250 miniature Long Long 560 long O male: Xm/Y and female X* /X* male: X* / Y and female Xm /x O male: X* /Y and female X* /X* male: Xm/Y and female Xm /x+arrow_forwardIN DROSOPHILA, AN X-LINKED RECESSIVE MUTATION, Xm CAUSES MINIATURE WINGS. LIST THE F₂ PHENOTYPIC RATIOS IF: A MINIATURE-WINGED FEMALE IS CROSSED WITH A NORMAL MALE AND A MINIATURE-WINGED MALE IS ● ● CROSSED WITH A NORMAL FEMALE. WHAT WOULD THE PHENOTYPIC RATIO FROM (A) BE IF THE MINIATURE- WINGED GENE WERE AUTOSOMAL? ASSUME IN ALL CASES THAT THE P1 INDIVIDUALS ARE TRUE-BREEDING.arrow_forwardIn Drosophila, an X-linked recessive mutation, Xm causes miniature wings. List the F2 phenotypic ratios if: a miniature-winged female is crossed with a normal male and a miniature-winged male is crossed with a normal female. What would the phenotypic ratio from (a) be if the miniature-winged gene were autosomal? Assume in all cases that the P1 individuals are true-breeding.arrow_forward
- Pigment in the mouse is produced only when the C allele is present.Individuals of the cc genotype have no color. If color is present,it may be determined by the A and a alleles. AA or Aa resultsin agouti color, whereas aa results in black coats.(a) What F1 and F2 genotypic and phenotypic ratios areobtained from a cross between AACC and aacc mice?(b) In the three crosses shown here between agouti femaleswhose genotypes were unknown and males of the aaccgenotype, what are the genotypes of the female parents foreach of the following phenotypic ratios? (1) 8 agouti (2) 9 agouti (3) 4 agouti8 colorless 10 black 5 black 10 colorlessarrow_forwardIn the Manx tailless phenotype of cats, the tailless phenotype is caused by the mutation ML and is inherited as an autosomal dominant trait. Homozygotes for ML are lethal, and do not survive to birth. A breeder mates a Manx tailless male with a Manx tailless female. The female is now pregnant with a litter of 3 kittens. What is the probability that all the kittens born will be tailless? 0.012 0.125 0.04 0.20 0.30arrow_forwardIn mice, the wild-type coat color, agouti (AA) [left mouse], is dominant to solid-colored, black fur (aa) [middle mouse]. However, a separate gene (C) is necessary for pigment production. A mouse that is homozygous for a recessive c allele at this locus is unable to produce pigment and is albino [right mouse] regardless of the allele present at locus A. Thus, the following genotypes are listed with their associated phenotypes: ~ A/A; C/C or A/A; C/c or A/a; C/C or A/a; C/c ==> "agouti" ~ a/a; C/C or a/a; C/c ==> "black" ~ A/A; c/c or A/a; c/c or a/a; c/c or a/a; c/c ==> "albino" This is an example of recessive epistasis, in which the recessive c allele "stands upon" the possible genotypes for the A gene (A/A, A/a, or a/a). If two agouti mice with the A/a; C/c genotype are mated, what is the expected phenotypic ratio in their offspring? A.9 albino, 4 agouti, 3 black B. 9 agouti, 4 albino, 3 black C.9 black, 4 albino, 3 agouti D.9 agouti, 4 black, 3 albinoarrow_forward
- A standard three-point mapping is conducted for recessive mutations in autosomal genes purple eye (pr), curved wing ( c) and black body (b). Their wild type alleles are also used for genetic mapping. An F1 Drosophila female heterozygous for purple eye (pr), curved wing (c) and black (b) is crossed to a triply homozygous mutant male. The observed numbers and phenotypes of the offspring are as follows: 360 pr c b 380 pr+ c+ b+ 104 pr c+ b 96 pr+ c b+ 30 pr c b+ 20 pr+ c+ b 6 pr c+ b+ 4 pr+ c b PROVIDE THE FOLLOWING: A) State the order of genes on this chromosome. B) Calculate map distances between the gene pairs: pr-c, pr-b, c-b. Show calculations, state the number of map units and which gene pairs they refer to.arrow_forwardTwo unlinked loci effect mouse hair color. AA or Aa mice are agouti. Mice with genotype aa are albino because all pigment production and deposition of pigment in hair is blocked. At the second locus, the B allele (black agouti coat) is dominant to the b allele (brown agouti coat). A mouse with an unknown genotype is mated with an albino mouse of genotype bbaa. Half of the offspring are albino, one quarter are black agouti, and one quarter are brown agouti. What is the genotype of the unknown parent?arrow_forwardConsider the following three autosomal recessive mutations in Drosophila:vestigial wings (v); wild type is long (v+)black body color (b); wildtype is gray (b+)plum eyes (p); wildtype is red (p+)A vestigal, gray, red female (homozygous for all three genes) is crossed with a long wing, black, plum male (homozygous for all three genes). The F1 female progeny are mated with triple homozygous recessive males. Here is the phenotypic data for the F2 progeny:vestigal; gray; red 580long wings; black; plum 592vestigal; black; red 45long; gray; plum 40vestigal; black; plum 89long; gray; red 94vestigal; gray; plum 3long; black; red 5A total of 1448 progeny were counted.Which one of the following values is the approximate distance between the plum eye color and black body color loci?arrow_forward
- In Drosophila, the dominant Bar mutation (B, chromosome X, position 57) results in thin bar- shaped eyes, while the recessive singed (sn, chromosome X, position 21) results burnt looking bristles. True breeding, wild type females are mated with true breeding males with Bar eyes and singed bristles. Using Drosophila notation, diagram the P1 and F1 crosses. P1 F1 Fill in the chart with phenotypic ratios that would be expected in the F2 generation. Use the space provided to show your work. Phenotype Females Males Overall (♀and ♂) =1 =1 =1arrow_forwardIn mice, the presence of a dominant A allele results in the agouti pattern of fur color, whereas the aa homozygous recessive results in a solid color pattern. The presence of another dominant B allele results in black fur color, whereas the homozygous recessive bb results in brown fur color. The presence of a third dominant C allele is required for any color to be observed (brown or black), whereas the homozygous recessive cc results in lack of any color whatsoever (albino). What is the phenotype of a mouse with the following genotype? Aa bb cc albino Agouti color pattern and brown Solid color pattern and brown Agouti color pattern and black Solid color pattern and blackarrow_forwardIn Drosophila, singed bristles (sn) and cut wings (ct) are both caused by recessive, X-linked alleles. The wild type alleles (sn+ and ct+) are responsible for straight bristles and intact wings, respectively. A female homozygous for sn and ct+ is crossed to a sn+ct male. The F1 flies are interbred. The F2 males are distributed as follows: genotype number sn ct 15 sn ct+ 34 sn+ ct 33 sn+ct+ 18 What is the map distance between sn and ct?arrow_forward
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