Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 3, Problem 43P
You have come into contact with two unrelated patients who express what you think is a rare
| a. | Given that this trait is rare, do you think the inheritance is dominant or recessive? |
| Are there any special conditions that appear to apply to the inheritance? | |
| b. | Which non-expressing members of these families must carry the mutant allele? |
| c. | If this trait is instead quite common in the population, what alternative |
| explanation would you propose for the inheritance? | |
| d. | Based on this new explanation in (c), which non-expressing members of these |
| families must have the genotype normally causing the trait? |
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Using the pedigree chart attached:
Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why?
Chapter 3 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 3 - For each of the terms in the left column, choose...Ch. 3 - In four-oclocks, the allele for red flowers is...Ch. 3 - The Aa heterozygous snapdragons in Fig. 3.3 are...Ch. 3 - In the fruit fly Drosophila melanogaster, very...Ch. 3 - A cross between two plants that both have yellow...Ch. 3 - In radishes, color and shape are each controlled...Ch. 3 - A wild legume with white flowers and long pods is...Ch. 3 - Prob. 8PCh. 3 - Assuming no involvement of the Bombay phenotype:...Ch. 3 - Several genes in humans in addition to the ABO...
Ch. 3 - Alleles of the gene that determines seed coat...Ch. 3 - Prob. 12PCh. 3 - In a population of rabbits, you find three...Ch. 3 - In clover plants, the pattern on the leaves is...Ch. 3 - Fruit flies with one allele for curly wings Cy and...Ch. 3 - Prob. 16PCh. 3 - In a species of tropical fish, a colorful orange...Ch. 3 - A rooster with a particular comb morphology called...Ch. 3 - A black mare was crossed to a chestnut stallion...Ch. 3 - Prob. 20PCh. 3 - Prob. 21PCh. 3 - a. How could you describe inheritance of flower...Ch. 3 - Explain the difference between epistasis and...Ch. 3 - The dominant allele H reduces the number of body...Ch. 3 - Secretors genotypes SS and Ss secrete their A and...Ch. 3 - Normally, wild violets have yellow petals with...Ch. 3 - Prob. 27PCh. 3 - Three different pure-breeding strains of corn that...Ch. 3 - In mice, the AY allele of the agouti gene is a...Ch. 3 - A student whose hobby was fishing pulled a very...Ch. 3 - Prob. 31PCh. 3 - Prob. 32PCh. 3 - Three genes in fruit flies affect a particular...Ch. 3 - The garden flower Salpiglossis sinuata painted...Ch. 3 - In foxgloves, there are three different petal...Ch. 3 - In a culture of fruit flies, matings between any...Ch. 3 - Suppose that blue flower color in a plant species...Ch. 3 - Prob. 38PCh. 3 - Considering your answers to Problem 38, does the...Ch. 3 - Prob. 40PCh. 3 - Prob. 41PCh. 3 - Familial hypercholesterolemia FH is an inherited...Ch. 3 - You have come into contact with two unrelated...Ch. 3 - Polycystic kidney disease is a dominant trait that...Ch. 3 - Using each of the seven coat color genes discussed...
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- Does the phenotype indicated by the red circles and squares in this pedigree show an inheritance pattern that is autosomal dominant, autosomal recessive, or X-linked?arrow_forwardYOUR SISTER DIED FROM TAY-SACHS DISEASE, INHERITED AS A RECESSIVE ALLELE (t). you're married and planning to start your family. you're worried about the disease and decide to have genetic testing to see if you or your spouse is a carrier of the tay-sachs allele. the test results show that you're a carrier of the allele, but your spouse isn't. what is the probability that you and your spouse will have a child with tay-sachs disease? show your work.arrow_forwardSickle cell anemia is a human genetic disorder caused by an autosomal recessive allele. A couple plan to marry and want to know the probability that they will have an affected child. With your knowledge of Mendelian inheritance, what can you tell them if (1) each has one affected parent and a parent with no family history of SCA or (2) the man is affected by the disorder but the woman has no family history of SCA?arrow_forward
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