Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 3, Problem 39P
Considering your answers to Problem 38, does the existence of a particular variation of a 9:3:3:1 ratio among the F2 progeny allow you to infer the operation of a specific biochemical mechanism responsible for these
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Consider two hypothetical recessive autosomal genes a and b, where a heterozygote is testcrossed to a double- homozygous mutant. Predict the phenotypic ratios under the following conditions: (a) a and b are located on separate autosomes. (b) a and b are linked on the same autosome but are so far apart that a crossover always occurs between them. (c) a and b are linked on the same autosome but are so close together that a crossover almost never occurs.
Susan’s grandfather was deaf, and passed down a hereditary form of deafness within Susan’s family as shown in Figure Q19–12.A. Is this mutation most likely to be dominant or recessive?B. Is it carried on an autosome or a sex chromosome? Why?C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and 7 unaffected). In comparing these 11 SNP results, how long a haplotype block would you expect to find around the critical gene? How might you detect it?
stion 6 of 18
Suppose that a geneticist discovers a new mutation in Drosophila melanogaster that causes the flies to shake and quiver.
She calls this mutation quiver, qu, and determines that it is due to an autosomal recessive gene. She wants to determine
whether the gene encoding quiver is linked to the recessive gene for vestigial wings, vg. She crosses a fly homozygous for
quiver and vestigial traits with a fly homozygous for the wild-type traits, and then uses the resulting F, females in a
testcross. She obtains the flies from this testcross.
Phenotype Number of flies
vg* qu+
230
vg qu
224
vg qut
vg* qu
97
99
Test the hypothesis that the genes quiver and vestigial assort independently by calculating the chi-squared, X², for this
hypothesis. Provide the X2 to one decimal place.
X2 =
Does the X value support the hypothesis that the quiver and vestigial genes assort independently? Why or why not?
the partial table of critical values for X2 calculations to test this hypothesis.
Chapter 3 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 3 - For each of the terms in the left column, choose...Ch. 3 - In four-oclocks, the allele for red flowers is...Ch. 3 - The Aa heterozygous snapdragons in Fig. 3.3 are...Ch. 3 - In the fruit fly Drosophila melanogaster, very...Ch. 3 - A cross between two plants that both have yellow...Ch. 3 - In radishes, color and shape are each controlled...Ch. 3 - A wild legume with white flowers and long pods is...Ch. 3 - Prob. 8PCh. 3 - Assuming no involvement of the Bombay phenotype:...Ch. 3 - Several genes in humans in addition to the ABO...
Ch. 3 - Alleles of the gene that determines seed coat...Ch. 3 - Prob. 12PCh. 3 - In a population of rabbits, you find three...Ch. 3 - In clover plants, the pattern on the leaves is...Ch. 3 - Fruit flies with one allele for curly wings Cy and...Ch. 3 - Prob. 16PCh. 3 - In a species of tropical fish, a colorful orange...Ch. 3 - A rooster with a particular comb morphology called...Ch. 3 - A black mare was crossed to a chestnut stallion...Ch. 3 - Prob. 20PCh. 3 - Prob. 21PCh. 3 - a. How could you describe inheritance of flower...Ch. 3 - Explain the difference between epistasis and...Ch. 3 - The dominant allele H reduces the number of body...Ch. 3 - Secretors genotypes SS and Ss secrete their A and...Ch. 3 - Normally, wild violets have yellow petals with...Ch. 3 - Prob. 27PCh. 3 - Three different pure-breeding strains of corn that...Ch. 3 - In mice, the AY allele of the agouti gene is a...Ch. 3 - A student whose hobby was fishing pulled a very...Ch. 3 - Prob. 31PCh. 3 - Prob. 32PCh. 3 - Three genes in fruit flies affect a particular...Ch. 3 - The garden flower Salpiglossis sinuata painted...Ch. 3 - In foxgloves, there are three different petal...Ch. 3 - In a culture of fruit flies, matings between any...Ch. 3 - Suppose that blue flower color in a plant species...Ch. 3 - Prob. 38PCh. 3 - Considering your answers to Problem 38, does the...Ch. 3 - Prob. 40PCh. 3 - Prob. 41PCh. 3 - Familial hypercholesterolemia FH is an inherited...Ch. 3 - You have come into contact with two unrelated...Ch. 3 - Polycystic kidney disease is a dominant trait that...Ch. 3 - Using each of the seven coat color genes discussed...
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