Study Guide for Campbell Biology
Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 43, Problem 20TYK
Summary Introduction

The complex system of the immune system includes special type of cells called lymphocytes. These lymphocytes are immune cells that act against infectious agents like bacteria, virus, and other pathogens. Lymphocytes are classified into two types namely B lymphocytes or B cell, and T lymphocytes or T cell based on the place where they are originated. B cells are synthesized in the bone marrow and T cells in the thymus. There is one more category in lymphocytes that includes natural killer cells.

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Which of the following statements regarding T cells activated by specific antigen is incorrect? a. They receive co-stimulatory signals through CD28. b. They suppress expression of sphingosine 1-phosphate (SIP). c. They take several days before differentiating into effector T cells. d. They cease to secrete and respond to interleukin-2 (IL-2). e. They begin to express CTLA4, which serves to limit T-cell proliferation.
Explain why each choice (a-d) is correct or incorrect. T cells are differentiated into two groups based on their glycoproteins CD4 or CD8.  Which of the following is true of CD4 T cells? a. They become cytotoxic T cells.  b. The become antigen presenting cells. c. They become T helper cells. d. They become plasma cells.
Which event happens first during cytotoxic T-cell activation? a. Cytotoxic T cells secrete perforin and granzyme. b. Cytotoxic T cells recognize foreign antigen presented on the surface of a MHC I molecule. c. Cytotoxic T cells proliferate to form many new cells specific for the same antigen d. Cytotoxic T cells recognize foreign antigen presented on the surface of a TCR.
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