Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 5, Problem 113P
Cancer
The Shanghai Women’s Health Study (SWHS) was undertaken to determine risk factor for different cancers among Asian women. The women were recruited from urban communities in 1997−2000 and were interviewed every 2 years to obtain health-related information.
One issue is whether risk prediction models derived from American populations are also applicable to Asian women.
Suppose the expected number of breast cancer cases among a large number of 45- to 49-year-old women in this study who were followed for 7 years is 149, while the observed number of cases is 107. Are there an unusually small number of cases among Asian women? Why or why not?
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Chapter 5 Solutions
Fundamentals of Biostatistics
Ch. 5.4 - What is the difference between a...Ch. 5.4 - Suppose a continuous random variable can only take...Ch. 5.4 - What is a standard normal distribution?Ch. 5.4 - (a) What is the area to the left of 0.2 under a...Ch. 5.4 - (a) What is z.30? What does it mean? (b) What is...Ch. 5.5 - What is the difference between a standard normal...Ch. 5.5 - What does the principle of standardization mean?Ch. 5.5 - Suppose the distribution of serum-cholesterol...Ch. 5.8 - Why do we use the normal approximation to the...Ch. 5.8 - Prob. C.2RE
Ch. 5.8 - The prevalence of glaucoma among the elderly in...Ch. 5.8 - The number of deaths from heart failure in a...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Suppose that total carbohydrate intake in 12- to...Ch. 5 - Suppose that total carbohydrate intake in 12- to...Ch. 5 - Suppose boys in this age range who live below the...Ch. 5 - Suppose boys in this age range who live below the...Ch. 5 - A study was conducted assessing the effect of...Ch. 5 - A study was conducted assessing the effect of...Ch. 5 - The duration of cigarette smoking has been linked...Ch. 5 - The duration of cigarette smoking has been linked...Ch. 5 - Serum cholesterol is an important risk factor for...Ch. 5 - Serum cholesterol is an important risk factor for...Ch. 5 - Serum cholesterol is an important risk factor for...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - In pharmacologic research a variety of clinical...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - Is the measure in Problem 5.38 a measure of...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - Refer to the pulmonary-function data in the Data...Ch. 5 - Prob. 43PCh. 5 - Refer to the pulmonary-function data in the Data...Ch. 5 - Prob. 45PCh. 5 - A clinical trial was conducted to test the...Ch. 5 - Well-known racial differences in blood pressure...Ch. 5 - Well-known racial differences in blood pressure...Ch. 5 - Prob. 49PCh. 5 - Suppose we observe 84 alcoholics with cirrhosis of...Ch. 5 - What is the probability of observing at least 29...Ch. 5 - Suppose we observe 84 alcoholics with cirrhosis of...Ch. 5 - FIGURE 5.22 Plasma-aldosterone concentrations in...Ch. 5 - FIGURE 5.22 Plasma-aldosterone concentrations in...Ch. 5 - Pregnant women with gestational diabetes mellitus...Ch. 5 - Officials in the State Health Department are...Ch. 5 - Prob. 57PCh. 5 - A study was conducted relating particulate air...Ch. 5 - Prob. 59PCh. 5 - Refer to Data Set VALID.DAT (at...Ch. 5 - Refer to Data Set VALID.DAT (at...Ch. 5 - Prob. 62PCh. 5 - A study concerned the risk of cancer among...Ch. 5 - Prob. 64PCh. 5 - A doctor diagnoses a patient as hypertensive and...Ch. 5 - A doctor diagnoses a patient as hypertensive and...Ch. 5 - Suppose the physician is not sure whether the...Ch. 5 - A study compared different treatments for...Ch. 5 - A study compared different treatments for...Ch. 5 - A study compared different treatments for...Ch. 5 - Obesity is an important determinant of...Ch. 5 - Prob. 72PCh. 5 - Prob. 73PCh. 5 - Prob. 74PCh. 5 - Prob. 75PCh. 5 - Prob. 76PCh. 5 - Answer the question in Problem 5.75 for a binomial...Ch. 5 - Prob. 78PCh. 5 - Prob. 79PCh. 5 - Prob. 81PCh. 5 - Prob. 82PCh. 5 - Prob. 83PCh. 5 - Prob. 85PCh. 5 - Retinitis pigmentosa (RP) is a genetic ocular...Ch. 5 - Prob. 87PCh. 5 - Prob. 88PCh. 5 - Prob. 89PCh. 5 - Physicians recommend that children with type-I...Ch. 5 - Physicians recommend that children with type-I...Ch. 5 - Prob. 92PCh. 5 - Prob. 93PCh. 5 - Prob. 94PCh. 5 - Prob. 95PCh. 5 - A previous study found that people consuming large...Ch. 5 - A previous study found that people consuming large...Ch. 5 - Prob. 98PCh. 5 - A study was recently published in Western...Ch. 5 - Prob. 100PCh. 5 - Prob. 101PCh. 5 - Prob. 102PCh. 5 - Prob. 103PCh. 5 - Prob. 104PCh. 5 - Prob. 105PCh. 5 - What is the 40th percentile of a normal...Ch. 5 - What is the sum of the 40th and 60th percentiles...Ch. 5 - What is z.90?Ch. 5 - A study was performed of different predictors of...Ch. 5 - A study was performed of different predictors of...Ch. 5 - Prob. 111PCh. 5 - Prob. 112PCh. 5 - Cancer The Shanghai Womens Health Study (SWHS) was...Ch. 5 - Prob. 114PCh. 5 - Prob. 115PCh. 5 - Prob. 116PCh. 5 - Prob. 117PCh. 5 - Prob. 118PCh. 5 - Prob. 119PCh. 5 - Prob. 120PCh. 5 - Prob. 121PCh. 5 - Prob. 122PCh. 5 - Prob. 123PCh. 5 - Prob. 124PCh. 5 - Hypertension Blood pressure readings are known to...Ch. 5 - Prob. 126PCh. 5 - Prob. 127PCh. 5 - Prob. 128PCh. 5 - Prob. 129PCh. 5 - Prob. 130P
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- Population Genetics In the study of population genetics, an important measure of inbreeding is the proportion of homozygous genotypesthat is, instances in which the two alleles carried at a particular site on an individuals chromosomes are both the same. For population in which blood-related individual mate, them is a higher than expected frequency of homozygous individuals. Examples of such populations include endangered or rare species, selectively bred breeds, and isolated populations. in general. the frequency of homozygous children from mating of blood-related parents is greater than that for children from unrelated parents Measured over a large number of generations, the proportion of heterozygous genotypesthat is, nonhomozygous genotypeschanges by a constant factor 1 from generation to generation. The factor 1 is a number between 0 and 1. If 1=0.75, for example then the proportion of heterozygous individuals in the population decreases by 25 in each generation In this case, after 10 generations, the proportion of heterozygous individuals in the population decreases by 94.37, since 0.7510=0.0563, or 5.63. In other words, 94.37 of the population is homozygous. For specific types of matings, the proportion of heterozygous genotypes can be related to that of previous generations and is found from an equation. For mating between siblings 1 can be determined as the largest value of for which 2=12+14. This equation comes from carefully accounting for the genotypes for the present generation the 2 term in terms of those previous two generations represented by for the parents generation and by the constant term of the grandparents generation. a Find both solutions to the quadratic equation above and identify which is 1 use a horizontal span of 1 to 1 in this exercise and the following exercise. b After 5 generations, what proportion of the population will be homozygous? c After 20 generations, what proportion of the population will be homozygous?arrow_forwardWhat term is used to express the likelihood of an event occurring? Are there restrictions on its values? If so, what are they? If not, explain.arrow_forward
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