Concept explainers
A study compared different treatments for preventing bone loss among postmenopausal women younger than 60 years of age [6]. The mean change in bone-mineral density of the lumbar spine over a 2-year period for women in the placebo group was −1.8% (a mean decrease), with a standard deviation of 4.3%. Assume the change in bone-mineral density is
Suppose 10% of the women assigned to the alendronate 5-mg group are actually not taking their pills (noncompliers). If noncompliers are assumed to have a similar response as women in the placebo group, what percentage of women complying with the alendronate 5-mg treatment would be expected to have a clinically significant decline? (Hint: Use the total-probability rule.)
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Chapter 5 Solutions
Fundamentals of Biostatistics
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