Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 5, Problem 45P
To determine
Explain the effect of each treatment regimen on the changes in the heart rate.
Check whether the distribution of changes is normal or not.
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The Diabetes Control and Complications trial research group, randomly assigned volunteers with type 1 (insulin-dependent) diabetes mellitus, but without retinopathy, either to a conventional treatment or to a more intensive treatment aimed at maintaining normal blood glucose levels. The volunteers' health was monitored closely for approximately six years. By the end of the study, 91 patients out of 378 in the conventional treatment group had developed retinopathy, whereas 23 out of 348 in the intensive treatment group had developed retinopathy. Test whether the rates of retinopathy differed significantly between the two treatment groups, if they did, which rate was significantly lower.
1. Provide the null hypothesis
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4. Identify the p-value for that test statistic
5. Using the p-value method and an alpha level of 0.02 state what your conclusions are regarding the null hypothesis, and…
The Diabetes Control and Complications trial research group, randomly assigned volunteers with type 1 (insulin-dependent) diabetes mellitus, but without retinopathy, either to a conventional treatment or to a more intensive treatment aimed at maintaining normal blood glucose levels. The volunteers' health was monitored closely for approximately six years. By the end of the study, 91 patients out of 378 in the conventional treatment group had developed retinopathy, whereas 23 out of 348 in the intensive treatment group had developed retinopathy. Test wether the rates of retionpathy differed significantly betweenthe two treatment groups, if they did, which rate was significantly lower.
1. Provide the null hypothesis
2. Provide the alternative hypotheses
3. calculate the appropriate test statistic. Show all work
4. Indentify the p-value for that test statistic
5. Using the p-vlaue method and an alpha level of 0.02 state what your conclusions is regarding the null hypothesis, and…
An experiment to determine if a migraine medication decreases a person's average number of monthly migraines is performed on 400 people who report they have several migraines a month. Researchers randomly assigned 200 people to the treatment group and 200 people to the control group. After the study, the researchers determined that 48 of the subjects in the treatment group and 28 of the subjects in the control group average fewer migraines per month. The data from the two groups are resampled 150 times, and the table shows the distribution of the differences of the proportions for the reconfigured treatment and control groups.
Chapter 5 Solutions
Fundamentals of Biostatistics
Ch. 5.4 - What is the difference between a...Ch. 5.4 - Suppose a continuous random variable can only take...Ch. 5.4 - What is a standard normal distribution?Ch. 5.4 - (a) What is the area to the left of 0.2 under a...Ch. 5.4 - (a) What is z.30? What does it mean? (b) What is...Ch. 5.5 - What is the difference between a standard normal...Ch. 5.5 - What does the principle of standardization mean?Ch. 5.5 - Suppose the distribution of serum-cholesterol...Ch. 5.8 - Why do we use the normal approximation to the...Ch. 5.8 - Prob. C.2RE
Ch. 5.8 - The prevalence of glaucoma among the elderly in...Ch. 5.8 - The number of deaths from heart failure in a...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Suppose that total carbohydrate intake in 12- to...Ch. 5 - Suppose that total carbohydrate intake in 12- to...Ch. 5 - Suppose boys in this age range who live below the...Ch. 5 - Suppose boys in this age range who live below the...Ch. 5 - A study was conducted assessing the effect of...Ch. 5 - A study was conducted assessing the effect of...Ch. 5 - The duration of cigarette smoking has been linked...Ch. 5 - The duration of cigarette smoking has been linked...Ch. 5 - Serum cholesterol is an important risk factor for...Ch. 5 - Serum cholesterol is an important risk factor for...Ch. 5 - Serum cholesterol is an important risk factor for...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - In pharmacologic research a variety of clinical...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - Is the measure in Problem 5.38 a measure of...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - Refer to the pulmonary-function data in the Data...Ch. 5 - Prob. 43PCh. 5 - Refer to the pulmonary-function data in the Data...Ch. 5 - Prob. 45PCh. 5 - A clinical trial was conducted to test the...Ch. 5 - Well-known racial differences in blood pressure...Ch. 5 - Well-known racial differences in blood pressure...Ch. 5 - Prob. 49PCh. 5 - Suppose we observe 84 alcoholics with cirrhosis of...Ch. 5 - What is the probability of observing at least 29...Ch. 5 - Suppose we observe 84 alcoholics with cirrhosis of...Ch. 5 - FIGURE 5.22 Plasma-aldosterone concentrations in...Ch. 5 - FIGURE 5.22 Plasma-aldosterone concentrations in...Ch. 5 - Pregnant women with gestational diabetes mellitus...Ch. 5 - Officials in the State Health Department are...Ch. 5 - Prob. 57PCh. 5 - A study was conducted relating particulate air...Ch. 5 - Prob. 59PCh. 5 - Refer to Data Set VALID.DAT (at...Ch. 5 - Refer to Data Set VALID.DAT (at...Ch. 5 - Prob. 62PCh. 5 - A study concerned the risk of cancer among...Ch. 5 - Prob. 64PCh. 5 - A doctor diagnoses a patient as hypertensive and...Ch. 5 - A doctor diagnoses a patient as hypertensive and...Ch. 5 - Suppose the physician is not sure whether the...Ch. 5 - A study compared different treatments for...Ch. 5 - A study compared different treatments for...Ch. 5 - A study compared different treatments for...Ch. 5 - Obesity is an important determinant of...Ch. 5 - Prob. 72PCh. 5 - Prob. 73PCh. 5 - Prob. 74PCh. 5 - Prob. 75PCh. 5 - Prob. 76PCh. 5 - Answer the question in Problem 5.75 for a binomial...Ch. 5 - Prob. 78PCh. 5 - Prob. 79PCh. 5 - Prob. 81PCh. 5 - Prob. 82PCh. 5 - Prob. 83PCh. 5 - Prob. 85PCh. 5 - Retinitis pigmentosa (RP) is a genetic ocular...Ch. 5 - Prob. 87PCh. 5 - Prob. 88PCh. 5 - Prob. 89PCh. 5 - Physicians recommend that children with type-I...Ch. 5 - Physicians recommend that children with type-I...Ch. 5 - Prob. 92PCh. 5 - Prob. 93PCh. 5 - Prob. 94PCh. 5 - Prob. 95PCh. 5 - A previous study found that people consuming large...Ch. 5 - A previous study found that people consuming large...Ch. 5 - Prob. 98PCh. 5 - A study was recently published in Western...Ch. 5 - Prob. 100PCh. 5 - Prob. 101PCh. 5 - Prob. 102PCh. 5 - Prob. 103PCh. 5 - Prob. 104PCh. 5 - Prob. 105PCh. 5 - What is the 40th percentile of a normal...Ch. 5 - What is the sum of the 40th and 60th percentiles...Ch. 5 - What is z.90?Ch. 5 - A study was performed of different predictors of...Ch. 5 - A study was performed of different predictors of...Ch. 5 - Prob. 111PCh. 5 - Prob. 112PCh. 5 - Cancer The Shanghai Womens Health Study (SWHS) was...Ch. 5 - Prob. 114PCh. 5 - Prob. 115PCh. 5 - Prob. 116PCh. 5 - Prob. 117PCh. 5 - Prob. 118PCh. 5 - Prob. 119PCh. 5 - Prob. 120PCh. 5 - Prob. 121PCh. 5 - Prob. 122PCh. 5 - Prob. 123PCh. 5 - Prob. 124PCh. 5 - Hypertension Blood pressure readings are known to...Ch. 5 - Prob. 126PCh. 5 - Prob. 127PCh. 5 - Prob. 128PCh. 5 - Prob. 129PCh. 5 - Prob. 130P
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