Chapter 5, Problem 55P

Pregnant women with gestational diabetes mellitus (GDM) are at risk for long-term weight gain and subsequent development of type II diabetes. A pilot weight loss clinical trial

Figure 5.22 Plasma-aldosterone concentrations in 53 Caucasian and 46 African American children. Values within the shaded area were undetectable (< 50 pmol/L). The solid horizontal lines indicate the mean values, and the broken horizontal lines indicate the mean ± se. The concept of standard error (se) is discussed in Chapter 6.

was conducted where women with GDM were randomized to either an active intervention using a web-based delivery or a control intervention (Nicklas et al. [3]). Women were randomized at 6 weeks postpartum and then were seen at follow-up visits at 6 months and 12 months postpartum. At 12 months postpartum, women in the active group lost a mean of 0.2 lb. with a standard deviation of 15.4 lbs.

percent of women in the active group were at or below their pre-pregnancy weight at 12 months postpartum? Hint: For all parts of this problem, assume that weights can be measured exactly and no continuity correction is necessary. At 12 months postpartum, women in the control group gained a mean of 7.9 lbs. with a standard deviation of 15.3 lbs. compared with their pre-pregnancy weight.

What are the approximate 10th and 90th percentiles of weight change from pre-pregnancy to 12 months postpartum among women in the active group? Among women in the control group?

Hint: Make the same assumptions as in Problems 5.53 and 5.54.

Officials in the State Health Department are considering using the active intervention in the general population of women with GDM. However, they expect that 80% of the women who are offered the intervention will actually comply with the intervention and are expected to have a weight gain distribution similar to the active group. The remaining 20% of women will lose interest and are expected to have a weight gain distribution similar to the control group.

If we assume that the change in weight from prepregnancy to 12 months is normally distributed, then what percent of women in the active group were at or below their pre-pregnancy weight at 12 months postpartum?

Hint: For all parts of this problem, assume that weights can be measured exactly and no continuity correction is necessary.

At 12 months postpartum, women in the control group gained a mean of 7.9 lbs. with a standard deviation of 15.3 lbs. compared with their pre-pregnancy weight.

4 What is the probability that a control group woman was at or below her pre-pregnancy weight at 12 months?

Hint: Make the same assumptions as in Problem 5.53.