Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 9, Problem 20RQ
Summary Introduction

To review:

The detailed structure of the pyruvate dehydrogenase complex.

Introduction:

Pyruvate gets converted to acetyl coenzyme (Co)Aunder anaerobic conditions. This CoA is oxidized to carbon dioxide in the tricarboxylic acid (TCA) cycle. The generation of adenosine triphosphate (ATP) occurs. The process occurs in the cytoplasm. A pyruvate transporter takes it to mitochondria. Pyruvate gets decarboxylated oxidatively. It forms acetyl CoA by the action of the pyruvate dehydrogenase complex (PDC).

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