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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 9, Problem 21QP
Textbook Problem
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In the most common form of cystic fibrosis, one amino acid is missing in the CF protein. Explain why none of the mutant protein product ends up in the cell’s plasma membrane.

Summary Introduction

To explain: The reason which elaborates that none of the mutant protein product ends up in the cell’s plasma membrane during the cystic fibrosis.

Introduction: The cystic fibrosis is a disorder that mainly affects the lungs, but it also affects the liver, pancreas, and kidneys. The person having cystic fibrosis will have difficulty in breathing due to the development of mucus in the lungs.

Explanation of Solution

In cystic fibrosis disease, the defective protein that is coded by a gene is marked for destruction before that protein reaches the plasma membrane. In return, a normal protein arrives at the plasma membrane to regulate the flow of ions through the plasma mem...

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