Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 10, Problem 3Q
Summary Introduction

To review:

An increase in the proton concentration of the suspension of submitochondrial particles will lead to adenosine triphosphate(ATP) synthesis.

Introduction:

An electron transport chain is a series of reactions where electrons aretransferred from electron donors to electron acceptors. This reaction requires the protons being transferred across the inner membrane of mitochondria. This causes a gradient of a proton whichhelps in the synthesis of the ATP molecule.

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A suspension of inside-out submitochondrial particles (i.e., the F1 unit is on the outside of the particle) is placed in a solution that contains ADP, Pi, and NADH. Will increasing the proton concentration of the solution result in ATP synthesis? Explain.
wouldn't ADP, a reactant of the other (phosphorylating) pathway, tend to inhibit the competing non-phosphorylating pathway (in order to get more ATP made)? And the reverse for ATP (whose presence indicates that pathway may not be needed any more)?
Why does removing a phosphate group from the triphosphate tail in a molecule of ATP release energy?
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