Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 10, Problem 17RQ
Summary Introduction

To review:

The comparison between the energy from one mole of glucose captured in glycolysis and in oxidative phosphorylation.

Introduction:

Glycolysis, as the term suggests, is the breakdown of a glucose molecule into two pyruvate molecules. This process occurs sequentially in steps and is catalyzed by different enzymes. Oxidative phosphorylation is a process that ends in the production of ATP by the oxidation of electron carriers. Glycolysis is a process that takes place inside the cytoplasm of the cell, while oxidative phosphorylation takes place in the mitochondria.

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Question 1: The overall process enabled by the glyoxylate cycle is: (2acetyl-CoA) + (NAD+) + (2H2O) → (succinate) + (2CoA) + (NADH) + (2H+) Dissect this process further by writing down all of the reactions that are actually involved in making one succinate from two acetyl-CoA units. Show chemical structure for all intermediates.
true or false:  Guanylate phosphorylase is responsible for converting guanosine monophosphate into guanosine diphosphate
Question 1: The 4 kinase steps in glycolysis are catalyzed by hexokinase, phosphofructokinase, phosphoglycerate kinase, and pyruvate kinase. Write each of these four reactions, including all participants. i. ii. iii. iv.
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