Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 10, Problem 61TQ
Summary Introduction

To review:

The inhibition of oxidative phosphorylation by rotenone that can take place when the substrate is pyruvate but not when succinate is used.

Introduction:

The oxidative phosphorylation is the mechanism by which the conservation of the adenosine triphosphate (ATP) generated by the electron transport chain (ETC) takes place due to the phosphorylation of adenosine diphosphate (ADP). There are many inhibitors of the ETC like antimycin A, rotenone, amyta, lnd azide. They can be used to determine the correct order of the ETC.

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