Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 11, Problem 7P
a. What letters are used to represent the short and long arms of human chromosomes? |
b. Sketch a schematic diagram of a hypothetical chromosome 3 that has 3 regions with 2 bands each on the short arm and 5 regions with 3 bands each on the long arm. Label the arms, regions, and bands and indicate a gene at position 3p32. |
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Chapter 11 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 11 - For each of the terms in the left column, choose...Ch. 11 - Many proteins other than histones are found...Ch. 11 - What difference is there in the compaction of...Ch. 11 - What is the role of the core histones in...Ch. 11 - a. About how many molecules of histone H2A would...Ch. 11 - The enzyme micrococcal nuclease can cleave...Ch. 11 - a. What letters are used to represent the short...Ch. 11 - About 2000 G bands are visible in a...Ch. 11 - Suppose you performed a fluorescence in situ...Ch. 11 - Which of the following would be suggested by a...
Ch. 11 - For each of the following pairs of chromatin...Ch. 11 - a. Drosophila b. Humans Give examples of...Ch. 11 - One histone modification that is seen consistently...Ch. 11 - Drosophila geneticists have isolated many...Ch. 11 - On the following figures, genes A and B are on the...Ch. 11 - Prob. 16PCh. 11 - The human genome contains about 3 billion base...Ch. 11 - Prob. 18PCh. 11 - Prob. 19PCh. 11 - Prob. 20PCh. 11 - Prob. 21PCh. 11 - If you are comparing the two telomeres in each...Ch. 11 - a. What DNA sequences are commonly found at human...Ch. 11 - Prob. 24PCh. 11 - Prob. 25PCh. 11 - Prob. 26PCh. 11 - Give at least one example of a chromosomal...Ch. 11 - a. Give at least three examples of types of...Ch. 11 - A number of yeast-derived elements were added to...Ch. 11 - Prob. 30P
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- ● ● Illustrate the chromosome changes in interphase and mitosis using a diploid cell that is 2n=4 (two large and two small chromosomes). Label the circles as G1 and G2 stages of interphase and each phase of mitosis (in order). Draw the chromosome in each circle using the following guidelines. 1) For unreplicated chromosome draw a line (/) and for replicated chromosome draw an X. 2) For simplicity, do not indicate that the chromosomes are decondensed chromatin during interphase. 3) Skip drawing the nuclear membrane or spindle fibers, since we are focusing on the chromosomes. Label genes in the resulting daughter cells as A/a and B/b. (These letters represent genes which are at particular places along the DNA molecule. Each chromosomes can have a thousand genes but we are focusing on these two.) Ask me Qs in class if anythign on this is not clear.arrow_forwardTwo chromosomes have the ff. order of genes: Normal Abnormal A B C centromere DEFGHI A B G F E D centromere C H I (a) Does the abnormal chromosome have a pericentric or paracentric inversion? Why? (b) Draw a sketch to show how these two chromosomes would pair during synapsis, showing all four strands. In your sketch, assume crossing over has occurred between genes E and F. Illustrate the germ cells produced at the end of Meiosis II and describe these germ cells.arrow_forwardIn Human chromosome 11 GC content is 42%. What is the percentage of each nucleotide on chromosome 11?arrow_forward
- b) please draw the inversion so i could imagine. thank you.arrow_forwardIn a germline progenitor cell before DNA replication (2N), a translocation occurred between a telocentric and submetacentric chromosome resulting in a translocation heterozygote. The location of the translocation is illustrated below. Draw the Prophase I pairing conformation that would result from this translocation. The four types of chromosomes you have now can be labeled as follows: T-WT (telocentric wild type), T-TL (telocentric translocation), SM-WT (submetacentric wild type), and SM-TL (submetacentric translocation). Using these labels, list (please do not draw) the possible outcomes of Anaphase I and the possible phenotypes for each outcome. Please explain your reasoning for each phenotype in a few words. asaparrow_forwardEach of the four types of structural chromosomal mutations is illustrated below. Label each picture with the type of chromosomal mutation that has occurred.arrow_forward
- Examine Figure . What type of chromosome (metacentric, submetacentric, acrocentric, or telocentric) is chromosome 1? What about chromosome 4?arrow_forward23 How would one best define the chromosomal location of a GENE? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a located on a single chromosome located oWa pair of homologous chromosomes located on multiple chromosomes d. located on a pair of non-homologous chromosomesarrow_forwardIdentify the chromosome rearrangement that occurred between the two homologous chromosomes shown on the left to give the chromosomes shown on the right. (The letters represent large regions of the chromsome.) A B с OOOO A B C deletion inversion deletion and insertion translocation D A B D A B CCDarrow_forward
- Please consider the figure below, parts A and B. A В Gene B Gene C Gene B Normal Gene A Chromosome 12 Normal Chromosome 1 Please consider figure A. a. Do these chromosomes come from a dividing or non-dividing cell? Give a reason for your answer. b. How many molecules of double stranded DNA will be present at anaphase I of a cell from this organism? Please consider figure B. A potentially carcinogenic mutation occurred on one of the chromosomes. The gene affected by the mutation codes for a protein involved in the repair of DNA damage. c. What is the correct term used to describe this chromosomal mutation? d. In terms of the development of cancer, is this a dominant or recessive mutation? e. What is the consequence of this mutation if it occurs during meiosis and is inherited by the offspring? Explain your answer in terms of the function of the protein.arrow_forwardIn the picture below, what is the name of the labelled part of the chromosome? Please explain its function in full detailarrow_forwardWhat is the specific base sequence found in human telomeres, and how does the base sequence contained in the telomeric regions of chromosomes differ from that found elsewhere in the chromosome? (Please indicate both the base sequence and the 5’/3’ polarity.)arrow_forward
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Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License