menu
bartleby
search
close search
Hit Return to see all results
close solutoin list

You are in charge of a new gene therapy clinic. Two cases have been referred to you for review and possible therapy. Case 1. A mutation in the promoter of a proto-oncogene causes the gene to make too much of its normal product, a receptor protein that promotes cell division. The uncontrolled cell division has caused cancer. Case 2. A mutation in an exon of a tumor-suppressor gene makes this gene nonfunctional. The product of this gene normally suppresses cell division. The mutant gene cannot suppress cell division, and this has led to cancer. What treatment options can you suggest for each case?

BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

Solutions

Chapter
Section
BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 12, Problem 18QP
Textbook Problem
16 views

You are in charge of a new gene therapy clinic. Two cases have been referred to you for review and possible therapy.

Case 1. A mutation in the promoter of a proto-oncogene causes the gene to make too much of its normal product, a receptor protein that promotes cell division. The uncontrolled cell division has caused cancer.

Case 2. A mutation in an exon of a tumor-suppressor gene makes this gene nonfunctional. The product of this gene normally suppresses cell division. The mutant gene cannot suppress cell division, and this has led to cancer. What treatment options can you suggest for each case?

Summary Introduction

To determine: The treatment options for a person experiencing mutation in the proto-oncogenes, resulting in the overexpression of the genes that can cause cancer.

Introduction: Cellular proto-oncogenes, more specifically “ras” genes, are primarily responsible for the translation of proteins that function as the signaling molecules for the initiation of the cell division. Mutation in these genes results in an overexpression of the proto-oncogenes which results in the overproduction of the promoting factors that are responsible for cell multiplication.

Explanation of Solution

The treatment method that can be suggested for a person experiencing mutation in the proto-oncogenes is drug therapy. In this therapy, the drug aims to target the promoter region of the proto-oncogenes...

Summary Introduction

To determine: The treatment options for a person experiencing mutation in the exon region of the tumor suppressor gene which makes the gene nonfunctional.

Introduction: Tumor-suppressor genes and proto-oncogenes together regulate the rate of cell division. Tumor suppressor gene code for proteins that suppresses the multiplication of the cells and proto-oncogenes promote multiplication of the cells. Mutation in the tumor suppressor gene results in the production of nonfunctional protein and the suppression mechanism of cell division also gets affected.

Still sussing out bartleby?

Check out a sample textbook solution.

See a sample solution

The Solution to Your Study Problems

Bartleby provides explanations to thousands of textbook problems written by our experts, many with advanced degrees!

Get Started

Chapter 12 Solutions

Human Heredity: Principles and Issues (MindTap Course List)
Show all chapter solutions
add

Additional Science Textbook Solutions

Find more solutions based on key concepts
Show solutions add
What is meant by biological evolution?

Human Biology (MindTap Course List)

Vitamin K can be made from exposure to sunlight. can be obtained from most milk products. can be made by digest...

Nutrition: Concepts and Controversies - Standalone book (MindTap Course List)

True or false? The plasma membrane is the outermost component of all cells. Explain.

Biology: The Unity and Diversity of Life (MindTap Course List)

A group of identical capacitors is connected first in series and then in parallel. The combined capacitance in ...

Physics for Scientists and Engineers, Technology Update (No access codes included)