To determine: The mutational event associated with the Burkitt’s lymphoma.
Introduction: Cancer is caused due to a mutation in the genome of the cells. The mutation can be of different types namely single
To determine: The chromosomes involved in tumor formation in Burkitt’s lymphoma.
Introduction: Several hereditary and environmental factors play a crucial role in the conversion of normal cells to cancerous cells. Factors associated with increasing the risk of developing cancer are smoking, UV radiations from the sun and viral infections. Genetic factors include inheritance of genes by the offspring’s that are mutated.
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Human Heredity: Principles and Issues (MindTap Course List)
- what would be the likely effect of a mutation that prevented the formation of memory cells?arrow_forwardWhat is the significance of the Philadelphia chromosome, and how is it related to leukemia?arrow_forwardWhat is the Philadelphia chromosome? Briefly describe how it causes chronic myeloid leukemia.arrow_forward
- 46. Explain why mutations in oncogenes are generally dominant while those in tumor suppressor genes are recessive.arrow_forwardWhich important characteristic of tumor cells did Otto Warburg discover?arrow_forwardhow are the hallmarks resisting cell death and enabling replicative immortality essential for cancer development. explain each in 3-5 sentences.arrow_forward
- Describe the mutational event that produces the MYC oncogene in Burkitt’s lymphoma. Why does the particular mechanism for generating oncogenic MYC result in a lymphoma rather than another type of cancer? Describe another mechanism for generating oncogenic MYC.arrow_forwardWhy is it harder to develop a drug that targets a tumor suppressor gene compared to an oncogene (limit 3-4 sentences)?arrow_forwardThe head of the oncology divison of a large biotech company proposes to develop a therapeutic antibody to treat cancers with mutant B-Raf oncogene. Is this a good idea? Why or why not(limit 3-4 sentences)?arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax