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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 12, Problem 21QP
Textbook Problem
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What mutational event is typically associated with Burkitt’s lymphoma? Which chromosomes are involved in this tumor?

Summary Introduction

To determine: The mutational event associated with the Burkitt’s lymphoma.

Introduction: Cancer is caused due to a mutation in the genome of the cells. The mutation can be of different types namely single nucleotide, substitutions, variations in the gene copy number, insertions, deletions, and chromosome rearrangements. Burkitt’s lymphoma is a cancer of immune cells, specifically B-cells. In this condition, the immune system of a person is left impaired.

Explanation of Solution

Burkitt’s lymphoma is the cancer of immune cells, specifically B-cells. This condition arises due to the translocation of a gene called c-myc. c-myc gene is responsible for ...

Summary Introduction

To determine:  The chromosomes involved in tumor formation in Burkitt’s lymphoma.

Introduction: Several hereditary and environmental factors play a crucial role in the conversion of normal cells to cancerous cells. Factors associated with increasing the risk of developing cancer are smoking, UV radiations from the sun and viral infections. Genetic factors include inheritance of genes by the offspring’s that are mutated.

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