Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 16, Problem 29P

Researchers know that Fru-M controls male sexual behavior in Drosophila because inappropriate Fru-M expression in females causes them to behave like males: Such females display male behaviors that are oriented toward other females.

a. Describe a fru mutation that could cause the expression of Fru-M in females.
b. Describe a transgene construct that scientists could generate and insert into Drosophila females that would have the same effect as the mutant you described in (a).
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Researchers know that Fru-M controls male sexualbehavior in Drosophila because inappropriate Fru-Mexpression in females causes them to behave likemales: Such females display male behaviors that areoriented toward other females.a. Describe a fru mutation that could cause the expression of Fru-M in females.b. Describe a transgene construct that scientistscould generate and insert into Drosophila femalesthat would have the same effect as the mutant youdescribed in (a).
A researcher has identified a mutant strain of yeast whose histones are unable to be acetylated. Which of the following is the MOST reasonable prediction for how the phenotype of this mutant yeast will differ from the phenotype of yeast cells with acetylated histones? A. The mutant will grow more rapidly. B. The mutant will grow much more slowly. C. The mutant will show decreased levels of gene expression. D. The mutant will show increased levels of gene expression.
Gene X is expressed in the developing brain, heart, andlungs of mice. Mutations that selectively affect gene Xfunction in these three tissues map to three differentregions (A, B, and C, respectively) 5′ of the X codingregion.a. Explain the nature of these mutations.b. Draw a map of the X locus consistent with the preceding information.c. How would you test the function of the A, B, and Cregions?

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Genetics: From Genes to Genomes, 5th edition

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