Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 16, Problem 19P

Follow the expression of a paternally imprinted gene through three generations. Indicate whether the copy of the gene from the male in generation I in the accompanying diagram is expressed in the germ cells and somatic cells of the individuals listed.

a. generation I male (I-2): germ cells
b. generation II daughter (II-2): somatic cells
c. generation II daughter (II-2): germ cell
d. generation II son (II-3): somatic cells
e. generation II son (II-3): germ cells
f. generation III grandson (III-1): somatic cells
g. generation III grandson (III-1): germ cells
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Categorize each of the following events as an example of genetic inheritance or epigeneticinheritance. a. For a line of liver cells growing in a laboratory, a gene encoding an immune cytokine isfound in compact chromatin.b. A chromosomal rearrangement in a blood stem cell leads to leukemia.c. Haploid bees are male, and diploid bees are female.d. Among genetically identical lab mice, those exposed to cigarette smoke have a higherrate of developing lung tumors
In humans, dosage compensation is accomplished by:  inactivating one X chromosome in female somatic cells  inactivating one homolog from each homologous pair of chromosomes in female somatic cells  inactivating the Y chromosome in male somatic cells  increasing gene expression from the X chromosome in male somatic cell
Use the dropdowns to indicate the pattern of methylation and gene expression expected for a maternally-imprinted gene in the somatic cell of a male individual. The Somatic cell would show [Select] male's male parent, and [Select] male's female parent. As a result, [Select] of the allele inherited from the of the allele inherited from the could be expressed. The pattern of methylation would be [Select] imprinted gene in a somatic cell of a female individual. for the same maternally-

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Genetics: From Genes to Genomes, 5th edition

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QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY