Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 16, Problem 4CONQ
What is the key difference between
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A gene, which we will call gene C, can be epigenetically modified in such a way that its expression in some cells is permanently silenced. Describe how you could conduct cell-fusion experiments to determine if a cis- or a trans-epigenetic mechanism is responsible for maintaining the silencing of gene C.
What makes X inactivation an epigenetic phenotype?
Using coat color in mice and the development of female honeybees as examples, explain how dietary factors can cause epigenetic modifications, leading to phenotypic effects.
Chapter 16 Solutions
Genetics: Analysis and Principles
Ch. 16.1 - Which of the following are examples of molecular...Ch. 16.1 - 2. An epigenetic modification to a specific gene...Ch. 16.1 - Prob. 3COMQCh. 16.1 - Epigenetic changes may a. be programmed during...Ch. 16.2 - 1. For the Igf2 gene, where do de novo methylation...Ch. 16.2 - 2. For XCI to occur, where are the Xist and Tsix...Ch. 16.2 - 3. Which of the following possibilities could...Ch. 16.3 - 1. Which of the following statements about...Ch. 16.3 - The effects of paramutation may vary with regard...Ch. 16.4 - 1. When mice carrying theallele exhibit a darker...
Ch. 16.4 - 2. If the VIN3 gene had a loss-of-function...Ch. 16.5 - Prob. 1COMQCh. 16.5 - Prob. 2COMQCh. 16 - Prob. 1CONQCh. 16 - List and briefly describe five types of molecular...Ch. 16 - Prob. 3CONQCh. 16 - What is the key difference between cis and...Ch. 16 - Prob. 5CONQCh. 16 - Prob. 6CONQCh. 16 - 7. Outline the molecular steps in the process of...Ch. 16 - Prob. 8CONQCh. 16 - 9. In general, explain how epigenetic...Ch. 16 - 10. What are the contrasting roles of trithorax...Ch. 16 - Describe the molecular steps by which polycomb...Ch. 16 - Prob. 12CONQCh. 16 - Using coat color in mice and the development of...Ch. 16 - How can environmental agents that do not cause...Ch. 16 - Prob. 15CONQCh. 16 - Prob. 16CONQCh. 16 - Explain how the VIN3/PRC2 complex specifically...Ch. 16 - Prob. 1EQCh. 16 - In the experiments described in Figure 16.8,...Ch. 16 - Prob. 3EQCh. 16 - A research study indicated that an agent in...Ch. 16 - Lets suppose you were interested in developing...Ch. 16 - Prob. 6EQCh. 16 - Prob. 7EQCh. 16 - 2. Discuss the similarities and differences of...
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- Using coat color in mice and the development of female honeybees as examples, explain how dietary factors cause epigenetic modifications and thereby lead to phenotypic effects.arrow_forwardIs paramutation a cis- or a trans-epigenetic mechanism?arrow_forwardIs RNA silencing an environmentally-induced epigenetic change? Explain.arrow_forward
- An epigenetic study of maternal care in mice was used to study transgenerational epigenetic inheritance. This study found that A. Increased maternal care during childhood resulted in lower stress levels as adults and decreased maternal care with their own offspring B. Increased maternal care during childhood resulted in lower stress levels as adults and increased maternal care with their own offspring. C. Increased maternal care during childhood resulted in higher stress levels as adults and decreased maternal care with their own offspring. D. Increased maternal care during childhood resulted in higher stress levels as adults and increased maternal care with their own offspring.arrow_forwardIf p63 can bind to the same promoter elements as p53, why would it be considered an inhibitor of p53? Can you clarify this relationship a bit?arrow_forwardWhat is the difference between silencing genes by imprintingand silencing by epigenetic modifications?arrow_forward
- In general, explain how epigenetic modifications are an important mechanism for developmental changes that lead to specialized body parts and cell types. How do the trithorax and polycomb group complexes participate in thisprocess?arrow_forwardWhat condition must be fulfilled in order for histone modification to be considered an epigenetic phenomenon? Does DNA methylation meet that criterion? Explain.arrow_forwardWhat is epigenetics and what are the three major epigenetic modification mechanisms?arrow_forward
- List and briefly describe five types of molecular mechanisms thatmay underlie epigenetic gene regulation.arrow_forward"Tobacco smoking triggers a large number of somaticmutations and epigenetic changes". Define about this ?arrow_forwardIn one cell, gene C is expressed, whereas in another cell, geneC is inactive. After the cells are fused experimentally, both copiesof gene C are expressed. This observation could be explained bya. a cis-epigenetic mechanism.b. a trans-epigenetic mechanism.c. DNA methylation.d. both a and b.arrow_forward
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