Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 16.1, Problem 3COMQ
Summary Introduction
Introduction:
Trans-generational epigenetic inheritance showed that there are generally two different types of epigenetic changes that can be observed, which are cis- epigenetic mechanism and trans-epigenetic mechanism. These differ because of their epigenetic modification of specific genes. The genes that cause modifications occur in multiple copies.
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Students have asked these similar questions
Which of the following is NOT a description of an epigenetic modification?
A. regulatory patterns that persisis in the absence of the original signal
B. stable alterations in gene expression without changes to the underlying DNA sequence
C. the persistence of gene expression patterns through cell division
D. an intrinsic signal that triggers cell differentiation
What degree of differences would you expect to see in the DNA base sequences and epigenetic marks of monozygotic twins?
a. Similar differences in DNA base sequence and epigenetic marks
b. Greater differences in DNA base sequence than epigenetic marks
c. Greater differences in epigenetic marks than DNA base sequence
d. No differences in either DNA base sequence or epigenetic marks
The key to epigenetic regulation is ________.
a.
controlling accessibility to transcription factors and RNA polymerase binding
b.
biochemical modification of binding factors
c.
physical modification of the DNA
Chapter 16 Solutions
Genetics: Analysis and Principles
Ch. 16.1 - Which of the following are examples of molecular...Ch. 16.1 - 2. An epigenetic modification to a specific gene...Ch. 16.1 - Prob. 3COMQCh. 16.1 - Epigenetic changes may a. be programmed during...Ch. 16.2 - 1. For the Igf2 gene, where do de novo methylation...Ch. 16.2 - 2. For XCI to occur, where are the Xist and Tsix...Ch. 16.2 - 3. Which of the following possibilities could...Ch. 16.3 - 1. Which of the following statements about...Ch. 16.3 - The effects of paramutation may vary with regard...Ch. 16.4 - 1. When mice carrying theallele exhibit a darker...
Ch. 16.4 - 2. If the VIN3 gene had a loss-of-function...Ch. 16.5 - Prob. 1COMQCh. 16.5 - Prob. 2COMQCh. 16 - Prob. 1CONQCh. 16 - List and briefly describe five types of molecular...Ch. 16 - Prob. 3CONQCh. 16 - What is the key difference between cis and...Ch. 16 - Prob. 5CONQCh. 16 - Prob. 6CONQCh. 16 - 7. Outline the molecular steps in the process of...Ch. 16 - Prob. 8CONQCh. 16 - 9. In general, explain how epigenetic...Ch. 16 - 10. What are the contrasting roles of trithorax...Ch. 16 - Describe the molecular steps by which polycomb...Ch. 16 - Prob. 12CONQCh. 16 - Using coat color in mice and the development of...Ch. 16 - How can environmental agents that do not cause...Ch. 16 - Prob. 15CONQCh. 16 - Prob. 16CONQCh. 16 - Explain how the VIN3/PRC2 complex specifically...Ch. 16 - Prob. 1EQCh. 16 - In the experiments described in Figure 16.8,...Ch. 16 - Prob. 3EQCh. 16 - A research study indicated that an agent in...Ch. 16 - Lets suppose you were interested in developing...Ch. 16 - Prob. 6EQCh. 16 - Prob. 7EQCh. 16 - 2. Discuss the similarities and differences of...
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- Which of the following is not a major mechanism of epigenetic change? a. DNA methylation b. Alteration of a DNA base sequence in a promoter c. Histone acetylation d. Action of RNA moleculesarrow_forwarda) What is a gene promoter? b) What proteins bind to a promoter? c) What do those proteins do to control gene expression?arrow_forwardWhich of the following is an example of epigenetic modulation? a) Ionization-induced DNA damage b) Single nucleotide polymorphism (SNP) c) Free-radical induced DNA damage d) Histone modifications of DNAarrow_forward
- Epigenetic marks regulate gene expression. Which epigenetic mark is NOT associated with positive gene expression? A. Histone acetylation B. Histone Methylation C. De-methylated DNA D. Methylated DNAarrow_forwardThe underlying cause(s) of epigenetic changes associated withcancer may bea. mutations in genes that encode chromatin-modifyingproteins.b. environmental agents that alter the function of chromatinmodifyingproteins.c. mutations in genes that encode proteins that directly acceleratecell growth.d. all of the above.e. both a and b.arrow_forwardEpigenetic changes maya. be programmed during development.b. be caused by environmental changes.c. involve changes in the DNA sequence of a gene.d. be both a and b.arrow_forward
- Insulators may exert their effect by a. acting as a barrier to changes in chromatin structure. b. blocking the effects of neighboring enhancers. c. doing both a and b. d. none of the above.arrow_forwardWhich of the following is not a possible outcome of changing the epigenetic code? a) exposure of regulatory region b) binding of transcription factors c) altered gene expression d) repositioning of nucleosomes by polymerasesarrow_forwardA gene, which we will call gene C, can be epigenetically modified in such a way that its expression in some cells is permanently silenced. Describe how you could conduct cell-fusion experiments to determine if a cis- or a trans-epigenetic mechanism is responsible for maintaining the silencing of gene C.arrow_forward
- A researcher has identified a mutant strain of yeast whose histones are unable to be acetylated. Which of the following is the MOST reasonable prediction for how the phenotype of this mutant yeast will differ from the phenotype of yeast cells with acetylated histones? A. The mutant will grow more rapidly. B. The mutant will grow much more slowly. C. The mutant will show decreased levels of gene expression. D. The mutant will show increased levels of gene expression.arrow_forwardA temperature-sensitive mutant allele of Ras causes the Ras protein to be fixed in the GDP-bound state at the nonpermissive temperature. What phenotype would you expect a cell homozygous for this mutation to have at the nonpermissive temperature? A.) It would stop dividing. B.) It would divide continuously. C.) It would divide normally.arrow_forwardDefine the following terms: a. epigenetics b. CpG island c. epimutation d. DNA methylation e. histone acetylationarrow_forward
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