Genetics: Analysis and Principles
Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 16, Problem 8CONQ
Summary Introduction

To review:

The process of gene silencing after X-chromosome inactivation (XCI) and give an example of a gene that does not get silenced.

Introduction:

XCI takes place to ensure that the gene expression in both the sexes, male and female, is equal. One of the two chromosomes in females gets heterochromatinized and forms a ‘Barr Body’. There is almost no expression of genes on this chromosome but sometimes, there might be some genes that show ‘leaky’ expression.

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Students have asked these similar questions
Following X-chromosome inactivation, most of the genes on theinactivated X chromosome are silenced. Explain how. Name onegene that is not silenced.
In X-chromosome inactivation, when is the choice made as to which X chromosome is inactivated? Does this choice occur in embryonic cells, in adult somatic cells, or both?
What is the spreading phase of X-chromosome inactivation? Whydo you think it is called a spreading phase?

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Genetics: Analysis and Principles

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY