Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 24.2, Problem 3COMQ
Summary Introduction
Introduction:
Bioinformatics is defined as a technique that utilizes computers and statistical data to interpret the biological information. Proteome is defined as the entire protein collection of an organism and the study of protein interactions is termed as Proteomics. Functional proteomics identifies the entire protein sequences of an organism. Functional genomics is defined as the technique that sequences the entire genome of an organism.
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A contig is
a. a set of molecular markers used in gene mapping.
b. a set of overlapping fragments that form a continuous stretch of DNA.
c. a set of fragments generated by a restriction enzyme.
d. a small DNA fragment used in sequencing.
Electrophoresis is a method used to sort proteins by their size. Why is a detergent added to the buffer?
a) Because SDS forms micelles in which the proteins can be transported through the gel in
b) Because SDS lowers the pH of the buffer
c) Because SDS denaturs the protein
d) Because smaller proteins move more slowly through the gel then
Place the following stages of a physical mapping study in theirmost logical order:A. Clone large fragments of DNA to make a BAC library.B. Determine the DNA sequence of subclones from a cosmidlibrary.C. Subclone BAC fragments to make a cosmid library.D. Subclone cosmid fragments for DNA sequencing.
Chapter 24 Solutions
Genetics: Analysis and Principles
Ch. 24.1 - 1. A DNA microarray is a slide that is dotted...Ch. 24.1 - 2. The purpose of a ChIP-chip assay is to...Ch. 24.1 - 3. For the method of RNA sequencing (RNA-Seq),...Ch. 24.1 - A gene knockout is a gene a. whose function has...Ch. 24.2 - Prob. 1COMQCh. 24.2 - Prob. 2COMQCh. 24.2 - Prob. 3COMQCh. 24.2 - Prob. 4COMQCh. 24.3 - Prob. 1COMQCh. 24.3 - 2. Homologous genes
a. are derived from the same...
Ch. 24.3 - Prob. 3COMQCh. 24 - 1. Give the meanings of the following terms:...Ch. 24 - Prob. 2CONQCh. 24 - What is a database? What types of information are...Ch. 24 - Prob. 4CONQCh. 24 - Prob. 5CONQCh. 24 - Prob. 6CONQCh. 24 - Prob. 7CONQCh. 24 - Prob. 8CONQCh. 24 - Prob. 1EQCh. 24 - In the procedure called RNA sequencing (RNA-Seq),...Ch. 24 - 3. Can two-dimensional gel electrophoresis be used...Ch. 24 - Prob. 4EQCh. 24 - 5. Describe the two general types of protein...Ch. 24 - 6. Discuss the bioinformatics approaches that can...Ch. 24 - 7. What is a motif? Why is it useful for computer...Ch. 24 - Discuss why it is useful to search a database to...Ch. 24 - Prob. 9EQCh. 24 - In this chapter, we considered a computer program...Ch. 24 - Prob. 11EQCh. 24 - Prob. 12EQCh. 24 - Prob. 13EQCh. 24 - Refer to question 3 in More Genetic TIPS before...Ch. 24 - Prob. 15EQCh. 24 - Prob. 16EQCh. 24 - 1. Let’s suppose you are in charge of organizing...
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- Discuss the process and give example on the following: a. Genome Project-write b. Mitochondrial DNA 'Spring Cleaning' c. Micro-encapsulation d. Specific Drug Targeting Answer a,b,c,darrow_forwardRefer to Figure 2 and compare this with the DNA model in Figure 1. a. In what ways are they similar? b. In what ways are they different? c. What is the biological significance of such differences? Why is the DNA referred to as the genetic material?arrow_forwardWhich type of genomics studies the transcripts and proteins expressed by a genome? a. Comparative genomics b. Structural genomics c. Proteogenomics d. Functional genomicsarrow_forward
- Explain how electrophoresis separates DNA strands. a. How is a DNA fingerprinting test interpreted? b. Define plasmid and how plasmids can change a bacteria’s activity. c. How do we digest/cleave plasmids? Explain the role of a restriction enzyme. d. Define sticky end and blunt end and which one is useful in molecular biology.arrow_forwardBioinformatics includes all of the following except (A) using computer programs to align DNA sequences. (B) using DNA technology to combine DNA from two different sources in a test tube. (C) developing computer-based tools for genome analysis. (D) using mathematical tools to make sense of biological systems.arrow_forwardIf DNA of a particular species was analyzed and it was found that it contains 27 percent A, what would be the percentage of C? a. 27 percent b. 30 percent c. 23 percent d. 54 percentarrow_forward
- If DNA of a particular species was analyzed and it was found that it contains 27 percent A, what would be the percentage of Carrow_forwardThis field of study examines the function and interaction of proteins within a cell or an organism. a. genomics b. bioengineering c. proteomics d. gene therapy e. None of these are correctarrow_forwardWhich of the following does not conform about Genetic Engineering? * a. used recombinant DNA (rDNA) technology b. direct manipulation of only one gene c. requires complex machinery and innovative minds d. process of manually transferring genetic informationarrow_forward
- What is the role of Sodium Iodidee in DNA isolation? A. Solubilization of phospholipids B Precipitation of DNA C Destroy hydrogen bonding network in solvent D Precipitation of cel wall and cell membranearrow_forwardA promoter is ______. a. a specific sequence of DNA nucleotides b. a specific sequence of RNA nucleotides c. a protein that binds to DNA d. an enzyme that synthesizes RNAarrow_forwardWhat method allows researchers to make a large amount of human proteins in bacteria? Select one: a. Shot gun sequencing b. Sequencing c. Southern blotting d. Gene cloning e. CRISPRarrow_forward
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