Genetics: Analysis and Principles
Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 24, Problem 16EQ
Summary Introduction

To review:

The way in which gene (Asparagine)Asn-141, (Isoleucine)Ile-141, and (Threonine)Thr-141 codons are arose. The six possible serine codons that are likely to be the primordial serine codon of globin gene family and the way codon gets changed to produce Asn-141, Ile-141 and Thr-141 codons.

Introduction:

In biological sciences, mutation is the change in the sequence of nucleotides of organism’s genome, extra chromosomal deoxyribonucleic acid (DNA), or virus. The mutation is caused due to an error during the replication of DNA or another kind of damages to the DNA, which may lead to an error during other repairs or may lead to an error during DNA replication.

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A. What amino acid sequence is encoded by the codon sequence AUAAUGGUAACGGUU? B. Suppose the codon sequence AGACACUCUAUUAAA has a single base pair mutation to AGACACUCUUUUAAA. If the old protein sequence was Arg-His-Ser-Ile-Lys, what will be the new sequence encoded by the mutant gene?
Suppose the codon sequence GCCAUUCAAGCGGAU has a single base pair mutation to GCCAUUCAAACgGAU. If the old protein sequence was Ala-Ile-Gln-Ala-Asp, what will be the new sequence encoded by the mutant gene? _________(Use the 3-letter amino acid abbreviations with hyphens and no spaces in between, i.e. Ser-Asn-Tyr-Le
TAT is a codon for the amino acid tyrosine (Tyr). If a mutation changes TAT to TAA, what kind of mutation has occured?
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