Concepts of Genetics (11th Edition)
Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 25, Problem 3NST

If the albino phenotype occurs in 1/10,000 individuals in a population at equilibrium and albinism is caused by an autosomal recessive allele a, calculate the frequency of:

  1. (a) The recessive mutant allele
  2. (b) The normal dominant allele
  3. (c) Heterozygotes in the population
  4. (d) Mating between heterozygotes
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Cystic fibrosis (CF) is a recessive autosomal disorder. In certain populations of Northern European descent, the number of people born with this disorder is about 1 in 2500. Assuming Hardy- Weinberg equilibrium for this trait: A. What are the frequencies for the normal and CF alleles? B. What are the genotype frequencies of homozygous normal, heterozygous, and homozygous affected individuals? C. Assuming random mating, what is the probability that two phenotypically unaffected heterozygous carriers will choose each other as mates?
Cystic fibrosis (CF) is a recessive autosomal disorder. In certainpopulations of Northern European descent, the number of peopleborn with this disorder is about 1 in 2500. Assuming Hardy-Weinberg equilibrium for this trait:A. What are the frequencies for the common (non-disease-causing)allele and the mutant (disease-causing) allele.B. What are the genotype frequencies of homozygous unaffected,heterozygous, and homozygous affected individuals?C. Assuming random mating, what is the probability that twophenotypically unaffected heterozygous carriers will chooseeach other as mates?
An autosomal locus has alleles A and a. We are given the frequency of individuals with the autosomal recessive phenotype. Which of the following statements is TRUE?  Choose all that are true. Note: HWE = Hardy-Weinberg equilibrium a) If we assume HWE, we can calculate both allele frequencies b) If we assume HWE, we can calculate the genotype frequencies that we weren't given c) We can calculate both allele frequencies even if we don't assume HWE d) We can calculate q = Freq(a) even if we don't assume HWE e) Even if we don't assume HWE, we can calculate the genotype frequencies that we weren't given

Chapter 25 Solutions

Concepts of Genetics (11th Edition)

Ch. 25 - The genetic difference between two Drosophila...Ch. 25 - The use of nucleotide sequence data to measure...Ch. 25 - The ability to taste the compound PTC is...Ch. 25 - Prob. 7PDQCh. 25 - What must be assumed in order to validate the...Ch. 25 - In a population where only the total number of...Ch. 25 - Determine whether the following two sets of data...Ch. 25 - If 4 percent of a population in equilibrium...Ch. 25 - Consider a population in which the frequency of...Ch. 25 - If the initial allele frequencies are p = 0.5 and...Ch. 25 - Under what circumstances might a lethal dominant...Ch. 25 - Assume that a recessive autosomal disorder occurs...Ch. 25 - One of the first Mendelian traits identified in...Ch. 25 - Describe how populations with substantial genetic...Ch. 25 - Achondroplasia is a dominant trait that causes a...Ch. 25 - Prob. 19PDQCh. 25 - Prob. 20PDQCh. 25 - A botanist studying water lilies in an isolated...Ch. 25 - A farmer plants transgenic Bt corn that is...Ch. 25 - In an isolated population of 50 desert bighorn...Ch. 25 - To increase genetic diversity in the bighorn sheep...Ch. 25 - What genetic changes take place during speciation?Ch. 25 - Some critics have warned that the use of gene...Ch. 25 - A form of dwarfism known as Ellisvan Creveld...Ch. 25 - Prob. 28ESPCh. 25 - What are the two groups of reproductive isolating...Ch. 25 - The original source of new alleles, upon which...Ch. 25 - A number of comparisons of nucleotide sequences...Ch. 25 - Shown below are two homologous lengths of the...Ch. 25 - Recent reconstructions of evolutionary history are...Ch. 25 - Prob. 34ESP
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