Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 25, Problem 26PDQ
Some critics have warned that the use of gene therapy to correct genetic disorders will affect the course of human evolution. Evaluate this criticism in light of what you know about population genetics and evolution, distinguishing between 9omatic gene therapy and germ-line gene therapy.
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Match the current applications to the appropriate branch of genetics. Not all applications will be placed.
Hereditary genetics
generating plasmids
from recombinant DNA
Population genetics
studying DNA-protein interactions
to understand gene regulation
researching gene transmission
to understand disease
tracing pedigrees to
determine patterns of gene
transmission within a family
Molecular genetics
studying the effects of natural
selection in many organisms
over the past million years
calculating genotype frequencies
to understand phenotype changes
in a population
Genetics is commonly seen as being grouped into several general areas: transmission, molecular, and population/evolution. Which biological processes are studied in transmission genetics?
The human genome has been fully mapped by the Human Genome Project. Information on the human genome is now freely available on DNA databases.
Which statement best describes an ethical issue concerning the Human Genome Project?
Responses
The money invested in this project can be utilized for other research.
The money invested in this project can be utilized for other research.
The complete information about the human genome can be utilized to map human ancestry.
The complete information about the human genome can be utilized to map human ancestry.
The complete information about the human genome can lead to devastating consequences on Earth’s biodiversity.
The complete information about the human genome can lead to devastating consequences on Earth’s biodiversity.
The human genome will provide information about inherited diseases, which raises the possibility of genetic manipulation in individuals.
Chapter 25 Solutions
Concepts of Genetics (11th Edition)
Ch. 25 - Prob. 1NSTCh. 25 - Prob. 2NSTCh. 25 - If the albino phenotype occurs in 1/10,000...Ch. 25 - A prospective groom, who is unaffected, has a...Ch. 25 - Prob. 1CSCh. 25 - Prob. 2CSCh. 25 - Prob. 3CSCh. 25 - HOW DO WE KNOW? Population geneticists study...Ch. 25 - CONCEPT QUESTION Read the Chapter Concepts list on...Ch. 25 - Price et al. [(1999).J. Bacteriol181:2358-2362)...
Ch. 25 - The genetic difference between two Drosophila...Ch. 25 - The use of nucleotide sequence data to measure...Ch. 25 - The ability to taste the compound PTC is...Ch. 25 - Prob. 7PDQCh. 25 - What must be assumed in order to validate the...Ch. 25 - In a population where only the total number of...Ch. 25 - Determine whether the following two sets of data...Ch. 25 - If 4 percent of a population in equilibrium...Ch. 25 - Consider a population in which the frequency of...Ch. 25 - If the initial allele frequencies are p = 0.5 and...Ch. 25 - Under what circumstances might a lethal dominant...Ch. 25 - Assume that a recessive autosomal disorder occurs...Ch. 25 - One of the first Mendelian traits identified in...Ch. 25 - Describe how populations with substantial genetic...Ch. 25 - Achondroplasia is a dominant trait that causes a...Ch. 25 - Prob. 19PDQCh. 25 - Prob. 20PDQCh. 25 - A botanist studying water lilies in an isolated...Ch. 25 - A farmer plants transgenic Bt corn that is...Ch. 25 - In an isolated population of 50 desert bighorn...Ch. 25 - To increase genetic diversity in the bighorn sheep...Ch. 25 - What genetic changes take place during speciation?Ch. 25 - Some critics have warned that the use of gene...Ch. 25 - A form of dwarfism known as Ellisvan Creveld...Ch. 25 - Prob. 28ESPCh. 25 - What are the two groups of reproductive isolating...Ch. 25 - The original source of new alleles, upon which...Ch. 25 - A number of comparisons of nucleotide sequences...Ch. 25 - Shown below are two homologous lengths of the...Ch. 25 - Recent reconstructions of evolutionary history are...Ch. 25 - Prob. 34ESP
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- BIOLOGY Give the SCOPE of the following fields in Applied Genetics: (SCOPE, not definition) 1. Epigenetics 2. Genomics 3. Metagenics 4. Genetic engineering 5. Phylogeneticsarrow_forwardDiscuss the impact of genetics in modern society. Cite specific examples.arrow_forwardFor each pair of individuals listed in the left column, select the description which best details the pair's contribution to genetics. 1. one gene - one enzyme hypothesis Beadle and Tatum 2. formula for the chance distribution of genotypes in natural populations Hardy and Weinberg 3. bacterial operons Jacob and Monod 4. phenomenon of sex linkagearrow_forward
- Is gene transfer a form of eugenics? Is it advantageous to use gene transfer to eliminate some genetic disorders? Can this and other technology be used to influence the evolution of our species? Should there be guidelines for the use of genetic technology to control its application to human evolution? Who should create and enforce these guidelines?arrow_forwardGive the scope of the following fields in Applied Genetics: Epigenetics Genomics Genetic Engineering Phylogenetics Metagenics take note that SCOPE is what I'm askingarrow_forwardYou are discussing with some of your bio major friends who have not taken Genetics and your non-bio major friends about how characteristics such as blue eye, light skin pigmentation, and light hair color, derived from a mutation that occurred about 10,000 years ago in Europe. Your friends are not very happy that you used the word mutation to describe the origin of human characteristics associated with light pigmentation. At that moment you only recall that green eye, fair skin and red hair in Neanderthals was due to other alleles and you mention that to them as an example of genetic determinants in species of the genus Homo. They are not convinced of your choice of the word mutation. Then you remember part of one of the papers that you read for Minicourse 5 regarding the OCA2 allele. “OCA2, homologous to the mouse pink-eyed dilution gene, encodes the human protein P, an integral membrane protein involved in both the transport of tyrosine and that helps in the regulation of…arrow_forward
- A.) Write a paragraph discussing the approach you would take to create a transgenic organism and the drawbacks to creating it. B.) Write comprehensively your answer about sequence events leading to evolution by natural selection.arrow_forwardThe Human Genome Project has demonstrated that in humans of all races and nationalities approximately 99.9 percent of the sequence is the same, yet different individuals can be identified by DNA fingerprinting techniques. What is one primary variation in the human genome that can be used to distinguish different individuals? Briefly explain your answer.arrow_forwardGenetic engineering utilized to create food sources has been said to be both like and unlike traditional breeding. One way it is different is: It mixes genes from different individuals of the same or similar species It involves whole organisms living in the field It selects from combinations of genes that come together on their own It mixes genes of different organisms such as viruses and crops, or spiders and goatsarrow_forward
- Humans and chimpanzees share about 98% of their DNA. What is DNA? What might be the role of regulatory genes in producing the anatomical differences between these two lineages? Give two examples of how the field of genetics has revolutionized biological science. What is polymerase chain reaction (PCR) and why is it important in genetics?arrow_forwardHereditary genetics Population genetics Molecular genetics Answer Bank expressing exogenous transgenes to understand function calculating genotype frequencies to understand phenotype changes in a population researching how genetic drift impacted many species over the past thousand years observing phenotypes in offspring to understand gene inheritance studying DNA-protein interactions to understand gene regulation tracing pedigrees to determine patterns of gene transmission within a familyarrow_forwardHow will you picture out the field of genetics will develop further in the future based on what has been achieved so far? Example of points to tackle: the rate of scientific and technological development limitations to what we should or should not do potential limitations of new applications from genetic discoveries how we understand the environment and ourselvesarrow_forward
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