Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 25, Problem 9PDQ
In a population where only the total number of individuals with the dominant
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Students have asked these similar questions
An autosomal locus has alleles A and a.
We are given the frequency of individuals with the autosomal recessive phenotype.
Which of the following statements is TRUE? Choose all that are true.
Note: HWE = Hardy-Weinberg equilibrium
a) If we assume HWE, we can calculate both allele frequencies
b) If we assume HWE, we can calculate the genotype frequencies that we weren't given
c) We can calculate both allele frequencies even if we don't assume HWE
d) We can calculate q = Freq(a) even if we don't assume HWE
e) Even if we don't assume HWE, we can calculate the genotype frequencies that we weren't given
In a hypothetical population of 2500 people, 2275 people have brown eyes and 225 people have blue eyes (the homozygous-recessive phenotype). If there are 4000 children produced by this generation, how many (i.e., what number) of the children would be expected to be heterozygous for eye color?
A given autosomal locus has three possible alleles (A1, A2, and A3). Assuming that the numbers of individuals with the six possible genotypes are as follows, what would be the frequency of the A1 allele in the population?
A1A1 = 30 A1A2 = 27 A2A2 = 12
A1A3 = 17 A2A3 = 10 A3A3 = 4
What would be the frequency of the A3A3 genotype? Assume the population is under Hardy-Weinberg equilibrium.
A.
0.182
B.
0.27
C.
0.03
D.
0.317
E.
0.107
F.
0.09
Chapter 25 Solutions
Concepts of Genetics (11th Edition)
Ch. 25 - Prob. 1NSTCh. 25 - Prob. 2NSTCh. 25 - If the albino phenotype occurs in 1/10,000...Ch. 25 - A prospective groom, who is unaffected, has a...Ch. 25 - Prob. 1CSCh. 25 - Prob. 2CSCh. 25 - Prob. 3CSCh. 25 - HOW DO WE KNOW? Population geneticists study...Ch. 25 - CONCEPT QUESTION Read the Chapter Concepts list on...Ch. 25 - Price et al. [(1999).J. Bacteriol181:2358-2362)...
Ch. 25 - The genetic difference between two Drosophila...Ch. 25 - The use of nucleotide sequence data to measure...Ch. 25 - The ability to taste the compound PTC is...Ch. 25 - Prob. 7PDQCh. 25 - What must be assumed in order to validate the...Ch. 25 - In a population where only the total number of...Ch. 25 - Determine whether the following two sets of data...Ch. 25 - If 4 percent of a population in equilibrium...Ch. 25 - Consider a population in which the frequency of...Ch. 25 - If the initial allele frequencies are p = 0.5 and...Ch. 25 - Under what circumstances might a lethal dominant...Ch. 25 - Assume that a recessive autosomal disorder occurs...Ch. 25 - One of the first Mendelian traits identified in...Ch. 25 - Describe how populations with substantial genetic...Ch. 25 - Achondroplasia is a dominant trait that causes a...Ch. 25 - Prob. 19PDQCh. 25 - Prob. 20PDQCh. 25 - A botanist studying water lilies in an isolated...Ch. 25 - A farmer plants transgenic Bt corn that is...Ch. 25 - In an isolated population of 50 desert bighorn...Ch. 25 - To increase genetic diversity in the bighorn sheep...Ch. 25 - What genetic changes take place during speciation?Ch. 25 - Some critics have warned that the use of gene...Ch. 25 - A form of dwarfism known as Ellisvan Creveld...Ch. 25 - Prob. 28ESPCh. 25 - What are the two groups of reproductive isolating...Ch. 25 - The original source of new alleles, upon which...Ch. 25 - A number of comparisons of nucleotide sequences...Ch. 25 - Shown below are two homologous lengths of the...Ch. 25 - Recent reconstructions of evolutionary history are...Ch. 25 - Prob. 34ESP
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- If the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by a rare clinically relevant allele is 1/8500 in a given population, what is the carrier frequency? Please give your answer as a percentage to 3 decimal places, do not include the % symbol. ANSWER: In a population where the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by only one known mutation is 1/8500 the carrier frequency is a percent.arrow_forwardThis lab exercise requires that we count certain Mendelian traits among students present in the lab. Your professor will explain each trait being addressed and will then ask students to identify if they are dominant or recessive for that specific trait. The collected traits will then be plugged into the Hardy-Weinberg Equilibrium formula in order to calculate frequency of Homozygous dominant, Heterozygous and Homozygous recessive individuals in the same. p2 + 2pq + q2 = 100 given data: trait: hair swirl 19 individuals total. 10 had the homozygous dominant hair swirl trait: clockwise the nine other were recessive please do a step by step explanation with the calculation using this data, as I am very unfamiliar with what values mean what and the equation itself thank you!arrow_forwardCystic fibrosis (CF) is a recessive autosomal disorder. In certain populations of Northern European descent, the number of people born with this disorder is about 1 in 2500. Assuming Hardy- Weinberg equilibrium for this trait: A. What are the frequencies for the normal and CF alleles? B. What are the genotype frequencies of homozygous normal, heterozygous, and homozygous affected individuals? C. Assuming random mating, what is the probability that two phenotypically unaffected heterozygous carriers will choose each other as mates?arrow_forward
- In a population of 200 people, an allele F has a frequency of 84%. What is the frequency of allele f? Using the Hardy-Weinberg equation, estimate the numbers of homozygous dominant, heterozygous, and homozygous recessive genotypes. (Remember that the formula is: p2 + 2pq + q2 = 1, where p represents the dominant allele and q represents the recessive allele.) *Be sure to account for all 200 people in the population.arrow_forwardIf a particular population of diploid individuals is in equilibrium and contains 16% homozygous dominant individuals, 48% heterozygotes, and 36% homozygous recessive individuals, what is the frequency of the recessive allele in this population?arrow_forwardIn a human population, one of 25,000 babies is born with sickle cell anaemia. The baby is homozygous recessive (genotype yy). Calculate the following; (i) Frequency of the recessive allele. (ii) Frequency of the dominant allele. (iii) Calculate the number of carrier in 25,000 babies born.arrow_forward
- Why are monozygotic twins who are reared apart so useful in the calculation of heritability?arrow_forwardIn a certain population of frogs, 120 are green, 60 are brownish-green, and 20 are brown. The allele for brown is denoted GB, and the allele for green is designated GG. These two alleles are incompletely dominant to each other. What is the frequency of genotype GGGG in this population?arrow_forwardTay–Sachs disease is an autosomal recessive disorder. Among Ashkenazi Jews, the frequency of Tay–Sachs disease is 1 in 3600. Assuming the Ashkenazi population is in Hardy-Weinberg equilibrium, what proportion of the population is expected to be carriers (e.g. heterozygous) for the Tay–Sachs allele?arrow_forward
- A phenotypically normal couple has had one normal child and one child with cystic fibrosis, an autosomal recessive disease. What are the genotypes of the parents? What is the chance that their next child will be a carrier of cystic fibrosis?Many recessive traits are very rare in a population, but cystic fibrosis does not follow this pattern. In some populations, the frequency of carriers for cystic fibrosis is 1/35. Does this mean that cystic fibrosis is not more common in inbred mating, such as those between first cousins? Why or why not?arrow_forwardIf there are five alleles at a locus, how many genotypes can there be at this locus? How many different kinds of homozygotes can there be? How many genotypes and homozygotes can there be with eight alleles at a locus?arrow_forwardWhat is the frequency of the heterozygous genotype if the homozygous genotype frequencies are 0.1385 (BB) and 0.5897 (bb)?arrow_forward
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