Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 4, Problem 3P
Interpretation Introduction
Interpretation:
The percentage of all the bases in DNA that has 20 % of thymine should be determined.
Concept introduction:
According to Chargaff`s rule, concentration of molecules is equal to its base pair in DNA structure.
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Remember: Tautomers are structural isomers that differ from each other based on the position of the proton(s) and their double bonds.
( ) The nitrogenous bases of nucleic acids, which contain heterocyclic and analogous nuclei, can adopt different tautomeric forms involving multiple H+ that are exchangeable depending on the medium. In DNA, spontaneous formation of smaller tautomers appears to contribute to mutagenic errors during DNA replication, while in RNA, they seem to be related to increased structural and functional diversity of enzymes and RNA aptamers (research this and confirm if it is false or real)
( ) in relation to the figure, anomer 1 has beta stereochemistry with respect to the C anomeric of the pentose, and is making an N-glycosidic bond
( ) in relation to the figure, anomer 1 has alpha stereochemistry with respect to the C anomeric of the pentose, and is making an N-glycosidic bond
( ) In general, in naturally occurring nucleosides,…
May you please help me with this?
A sample of purified DNA was incubated with deoxyribonuclease (DNAse) at 37oC. An
aliquot was removed from the reaction mixture every minute for 5 minutes and
the A260 recorded. The following data were obtained.
Time (min) A260
0 0.60
1 0.64
2 0.67
3 0.70
4 0.72
5 0.73
Describe the action of deoxyribonuclease on DNA and explain the increase in
A260.
Calculating human genome
If 1.5 percent of the human genome consists of protein-coding sequences, and the entire genome has 3.2x10^9, how many codons are there in the human genome? Remember that a codon is three nucleotides in length.
Chapter 4 Solutions
Biochemistry
Ch. 4 - Prob. 1PCh. 4 - Prob. 2PCh. 4 - Prob. 3PCh. 4 - Prob. 4PCh. 4 - Prob. 5PCh. 4 - Prob. 6PCh. 4 - Prob. 7PCh. 4 - Prob. 8PCh. 4 - Prob. 9PCh. 4 - Prob. 10P
Ch. 4 - Prob. 11PCh. 4 - Prob. 12PCh. 4 - Prob. 13PCh. 4 - Prob. 14PCh. 4 - Prob. 15PCh. 4 - Prob. 16PCh. 4 - Prob. 17PCh. 4 - Prob. 18PCh. 4 - Prob. 19PCh. 4 - Prob. 20PCh. 4 - Prob. 21PCh. 4 - Prob. 22PCh. 4 - Prob. 23PCh. 4 - Prob. 24PCh. 4 - Prob. 25PCh. 4 - Prob. 26PCh. 4 - Prob. 27PCh. 4 - Prob. 28PCh. 4 - Prob. 29PCh. 4 - Prob. 30PCh. 4 - Prob. 31PCh. 4 - Prob. 32PCh. 4 - Prob. 33PCh. 4 - Prob. 34PCh. 4 - Prob. 35PCh. 4 - Prob. 36PCh. 4 - Prob. 37PCh. 4 - Prob. 38PCh. 4 - Prob. 39PCh. 4 - Prob. 40PCh. 4 - Prob. 41PCh. 4 - Prob. 42PCh. 4 - Prob. 43PCh. 4 - Prob. 44PCh. 4 - Prob. 45PCh. 4 - Prob. 46PCh. 4 - Prob. 47PCh. 4 - Prob. 48PCh. 4 - Prob. 49PCh. 4 - Prob. 50PCh. 4 - Prob. 51PCh. 4 - Prob. 52P
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- I'm having difficulty with some homework, 6. a. The double helical structure of DNA is intrinsically unstable and easily dissociates to form two separate strands. Why? How does this affect the two key biological functions of chromosomal DNA? What would happen if the DNA helices were too stable? b. How can one measure the stability of a particular duplex DNA? Which molecular properties affect the stability?arrow_forwardDNA Stability/Chapter 4 A solution of DNA contains two different DNA molecules. Molecule 1 is 500 base pairs and contains 100 A’s. Molecule 2 is 500 base pairs and contains 300 A’s. (1) How many AT base pairs and GC base pairs is in each DNA molecule? (2) How many, G’s, A’s, T’s and C’s are in each molecule? (3) Draw one figure that shows the relative melting temperature of the two DNA molecules.arrow_forwardDNA What do A and G have in common that is notably different from T and C?arrow_forward
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