Laboratory Manual for Human Anatomy
5th Edition
ISBN: 9781259683831
Author: Eric Wise, Kenneth S. Saladin Dr.
Publisher: McGraw-Hill Education
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Chapter 4.3, Problem 13BYGO
Summary Introduction
To determine:
The differences between mutation and nondisjunction.
Introduction:
The genetic disorders are the hereditary diseases that are passed on to the offsprings by the parent's defective genes. Some genetic disorders are caused due to the mutations in the DNA strands. Such defects are inherited only if they are passed in to germ cells. Examples of genetic disorders are Tay-Sachs disease, Huntington's disease, and Sickle cell anemia.
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Define a Point mutation and give an example.
What is sickle cell anemia and what causes it.
What is nondisjunction? How does nondisjunction cause disorders?
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Question 3
Explain briefly the meaning of this statement: Genetic information is encoded in the DNA molecule.
I have this textbook question in my grade 11 bio and it has me really confused as to where to start. Any help would be much appreciated
Examine the following DNA sequence and determine what type of mutation, if any, produced the sequences below: ...TAACGCATIT... (a) ...TAGGART... (b) ...TAG CAST... (c) ...TAG CATTLE... (d) ...TACGCA GT TT...
Chapter 4 Solutions
Laboratory Manual for Human Anatomy
Ch. 4.1 - Prob. 1BYGOCh. 4.1 - Prob. 2BYGOCh. 4.1 - Prob. 3BYGOCh. 4.1 - Describe two ways a fertilized egg prevents the...Ch. 4.2 - List the four primary tissue types of the adult...Ch. 4.2 - Oligohydramnios17 is an abnormally low volume of...Ch. 4.2 - Prob. 5BYGOCh. 4.2 - Prob. 6BYGOCh. 4.2 - Prob. 7BYGOCh. 4.2 - Prob. 8BYGO
Ch. 4.2 - Prob. 9BYGOCh. 4.2 - Prob. 10BYGOCh. 4.2 - Define and describe the neural tube, primitive...Ch. 4.3 - Prob. 1AWYKCh. 4.3 - Prob. 12BYGOCh. 4.3 - Prob. 13BYGOCh. 4.3 - Prob. 14BYGOCh. 4.3 - Answer the following questions to test your...Ch. 4 - Prob. 4.1.1AYLOCh. 4 - Prob. 4.1.2AYLOCh. 4 - Prob. 4.1.3AYLOCh. 4 - Prob. 4.1.4AYLOCh. 4 - Prob. 4.1.5AYLOCh. 4 - Prob. 4.1.6AYLOCh. 4 - Prob. 4.1.7AYLOCh. 4 - Prob. 4.1.8AYLOCh. 4 - The duration of pregnancy and how the date of...Ch. 4 - Prob. 4.2.2AYLOCh. 4 - Prob. 4.2.3AYLOCh. 4 - Prob. 4.2.4AYLOCh. 4 - Prob. 4.2.5AYLOCh. 4 - Prob. 4.2.6AYLOCh. 4 - Prob. 4.2.7AYLOCh. 4 - Prob. 4.2.8AYLOCh. 4 - Prob. 4.2.9AYLOCh. 4 - The major changes that occur during the embryonic...Ch. 4 - Prob. 4.2.11AYLOCh. 4 - How the coelom forms, how it divides into the...Ch. 4 - The meaning of organogenesis, and some tissues and...Ch. 4 - Prob. 4.2.14AYLOCh. 4 - Prob. 4.2.15AYLOCh. 4 - Prob. 4.2.16AYLOCh. 4 - Prob. 4.2.17AYLOCh. 4 - Prob. 4.2.18AYLOCh. 4 - Prob. 4.2.19AYLOCh. 4 - The three modes in which the conceptus is...Ch. 4 - The development and mature structure of the...Ch. 4 - The relationship of the placenta to the umbilical...Ch. 4 - Prob. 4.2.23AYLOCh. 4 - The time at which the individual is considered to...Ch. 4 - Prob. 4.2.25AYLOCh. 4 - Prob. 4.3.1AYLOCh. 4 - Prob. 4.3.2AYLOCh. 4 - Prob. 4.3.3AYLOCh. 4 - Clinical Perspectives (p. 100) The meaning of...Ch. 4 - Prob. 4.3.5AYLOCh. 4 - Prob. 4.3.6AYLOCh. 4 - Prob. 4.3.7AYLOCh. 4 - When a conceptus arrives in the uterus, it is at...Ch. 4 - The entry of a sperm nucleus into an egg must be...Ch. 4 - Prob. 3TYRCh. 4 - Prob. 4TYRCh. 4 - Which of these results from aneuploidy? Turner...Ch. 4 - Prob. 6TYRCh. 4 - Prob. 7TYRCh. 4 - Prob. 8TYRCh. 4 - Prob. 9TYRCh. 4 - For the first 8 weeks of gestation, a conceptus is...Ch. 4 - Viruses and chemicals that cause congenital...Ch. 4 - Prob. 12TYRCh. 4 - Prob. 13TYRCh. 4 - Prob. 14TYRCh. 4 - Prob. 15TYRCh. 4 - The enzymes with which a sperm penetrates an egg...Ch. 4 - Prob. 17TYRCh. 4 - Prob. 18TYRCh. 4 - Prob. 19TYRCh. 4 - Prob. 20TYRCh. 4 - Prob. 1BYMVCh. 4 - Prob. 2BYMVCh. 4 - Prob. 3BYMVCh. 4 - Prob. 4BYMVCh. 4 - Prob. 5BYMVCh. 4 - Prob. 6BYMVCh. 4 - Prob. 7BYMVCh. 4 - Prob. 8BYMVCh. 4 - Prob. 9BYMVCh. 4 - Prob. 10BYMVCh. 4 - Prob. 1TOFCh. 4 - Prob. 2TOFCh. 4 - Prob. 3TOFCh. 4 - Prob. 4TOFCh. 4 - Prob. 5TOFCh. 4 - Prob. 6TOFCh. 4 - Prob. 7TOFCh. 4 - Prob. 8TOFCh. 4 - Prob. 9TOFCh. 4 - Prob. 10TOFCh. 4 - Only one sperm is needed to fertilize an egg, yet...Ch. 4 - Prob. 2TYCCh. 4 - Prob. 3TYCCh. 4 - Prob. 4TYCCh. 4 - Prob. 5TYC
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- Question 1: Look at the following normal and mutant DNA sequences. Normal Sequence (5'-3'): ATG AAC GTT ATC GCA Mutated Sequence (5'-3'): ATG AAT GTC ATC GCA a) What type of mutation has occurred (be specific)? b) Fill in the table for the normal and mutated sequences. Starting with the given 5'-3' sequence, input the complementary DNA, transcribed RNA from the 3'-5' DNA and translated polypeptide sequence for both. Hint: use the codon table! Normal sequence Mutant sequence DNA 5'-3' (given) DNA 3'-5' RNA Polypeptide (use 3 letter codes) c) Based on parts A and B above, what is the ultimate effect this mutation has had on the polypeptide? (1 sentence summary)arrow_forwardThis is a homework question that I have on my Adv. Anatomy & Physiology assignment. How to I got about answering the question? (I do have the Codon table in my textbook) Consider a hypothetical protein that consists of the amino acid sequence arginine, phenylalanine and histidine. From this information, construct (1) the original DNA strand, (2) corresponding mRNA codons and (3) tRNA anticodons used to produce this hypothetical protein. (Only use 1 mRNA codon per amino acid.) In addition, be sure to include start and stop sequences where appropriate.arrow_forwardQuestion 3: Look carefully at the structures of the two molecules shown below and answer the following questions. O= ddCTP O= OH O 11 HO-P-O-P-O-P-O I OH OH NH₂ ddCMP O 11 HO-P-O OH NH₂ A) What would you expect to happen if you added ddCTP to a DNA synthesis reaction in vitro in large excess over the concentration of dCTP? B) What would happen if ddCTP were added at 10% of the concentration of dCTP? C) What effect would you expect if ddCMP were added to the synthesis in large excess over dCTP? At 10% of the concentration of dCTP?arrow_forward
- Which of the following statements regarding mutation is FALSE? Question options: mutations can be caused by certain environmental agents ALL of these statements are TRUE mutations are usually lethal to the organism mutations in somatic ells of multicellular organisms are not passed to offspring through sexual reproduction mutations typically occur during the production or repair of DNA mutations in bacteria are passed to daughter cells Question 3 A(n) _________ mutation involves the substitution of one purine for another purine. Question options: frameshift transversion transduction translocation transformation transitionarrow_forwardThe word mutation is generally considered to be negative. However, is there a positive side to mutations? Briefly explain your answer.arrow_forwardQuèstion 2 Which example is describing a "missense" mutation? O The normal amino acid sequence of a protein is Met-Ala-Phe-Tyr and the mutated alele produces an amino acid sequence Met-Ala-Phe-Tyr OThe normal amino acid sequence of a protein is Met-Ala-Phe-Tyr and the mutated allele produces an amino acid sequence Met-Ala-STOP O The normal amino acid sequence of a protein is Met-Ala-Phe-Tyr and the mutated allele produces an amino acid sequence Met-Ala-Phe-Leu AMoving to the next question preinarrow_forward
- The Effects of a Mutation are Difficult to Predict Why?arrow_forwardYou live in a community with cell sites (or cellular-based stations). Your mother thinks that this releases radiation that may harm your family. She plans to seek the help of the local government unit to request the removal of the cell site. 1. Is your mother's doubt valid? Explain. 2. How is the situation related to mutation?arrow_forwardQUESTION 5: Should PCR primers be complementary to each other? Explain the reasoning for your answer.arrow_forward
- Silent mutations that occur in DNA are quite common in living cells and usually involve no effects onphenotype. 3: Provide one example of a clinical implication of a “silent mutation” that proven to have an effect onthe phenotype and provide a brief description of its molecular characteristics?arrow_forwardFind non-cancerous, non--nonsense, point mutation genetic disease. Describe the disease's name and the type of mutation. Compare the gene sequence between wild type and mutant. Compare the polypeptide sequence and structure encoded by the wild type's gene and the mutant's gene. Describe and explain the consequences of the mutation to a patient's health. Note: 1. These questions will test the concepts of DNA-Protein transcription and translation on the effects of mutation. 2. Using dissimilar example/solution from your classmate and lecture's notes is encouraged. 3. Provide citation and reference.arrow_forwardLay out the genetics of Nicholas’s case, including where the mutationoccurred, what exact nucleotide defect was present, why this was aserious type of defect, and why he was so affected by the mutationbut his mother was not.arrow_forward
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