Genetic Analysis: An Integrated Approach (2nd Edition)
Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 5, Problem 12P

On the DrosophilaX chromosome, the dominant allele y+ produces gray body color and the recessive allele y producesyellow body. This gene is linked to one controlling full eye shape by a dominant allele lz+ and lozenge eye shape with arecessive allele lz . These genes recombine with a frequency of approximately 28% . The Lz gene is linked to gene F controlling bristle form, where the dominant is long bristlesand the recessive is forked bristles. The Lz and F genes recombine with a frequency of approximately 32% .

a. Using any genotypes you choose, design two separatecrosses, one to test recombination between genes Y and Lz and the second between genes Lz and F. Assume 1000 progeny are produced by each cross, and give thenumber of progeny in each outcome category. (In setting up your crosses, remember that Drosophila males do not undergo recombination.)

b. Can any cross reveal genetic linkage between gene Y and gene F? Why or why not?

c. Why is “independent assortment” the genetic term thatbest describes the observations of a genetic cross between gene Y and gene F?

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In Drosophila fruit flies, the genes for warped wings (dwp), rumpled bristles (rmp), and pallid wings (pld) are linked.    A trihybrid female for all three allleles is crossed with homozygous recessive male for all three alleles and the offspring obtained showed the following phenotypes: 3            pld     rmp    dwp 428        pld    rmp      + 427         +       +       dwp 48           +     rmp      + 47         pld      +       dwp 23         pld      +        + 2             +       +        + 22           +     rmp    dwp   What is the order and map distance between these three alleles?
In Drosophila, a cross was made between females expressing thethree X-linked recessive traits, scute bristles (sc), sable body (s),and vermilion eyes (v), and wild-type males. All females were wildtype in the F1, while all males expressed all three mutant traits.The cross was carried to the F2 generation and 1000 offspringwere counted, with the results shown in the following table. Nodetermination of sex was made in the F2 data. Question:Calculate the coefficient of coincidence; does this represent positive or negative interference? Phenotype Offspringsc s v                314+ + +               280+ s v                150sc + +             156sc + v               46+ s +                30sc s +               10+ + v                14
. In Drosophila, three loci, Bar eyes (B, dominant), Scalloped wings (sd, recessive), and tanbody (t, recessive) are all located on the X chromosome. Bar eyes is located at position57, scalloped wings at position 51.5, and tan body at position 27.5. A female whosemother was homozygous dominant at all three loci and whose father was hemizygousrecessive at all three loci produces 1000 egg cells. How many TsdB cells would youexpect if chromosomal interference = 0? ____6-7_______ why is that the answer?

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Genetic Analysis: An Integrated Approach (2nd Edition)

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