Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 5, Problem 8P
Gene G recombines with gene T at a frequency of
Assuming any desired genotype is available, propose a genetic cross whose result could be used to determine which of the proposed genetic maps is correct.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Explain why it is possible for the proband in the following pedigree to have children of blood types A, B, and AB. Considering epistatic genes, what are the possible genotypes of II-2?
A double heterozygote has the repulsion configuration Ab/aB of two linked genes that have a frequency recombination of 0.2. If a randomly chosen gamete carries A, what is the probability that it also carries B?
Please label the tetrad type in the table as PD (parental ditype), NPD (non parental ditype) or T (tetratype) and answer the following questions
a) Are the genes linked? Please explain SPECIFICALLY how you can distinguish between linked and unlinked genes in this instance.
b) If the two genes are linked, calculate the % recombination between ser and thr. Show the formula used, as well as all of your calculations.
c) Draw a single map illustrating the arrangement of the two genes on the chromosome with respect to each other and to the centromere of the chromosome. Make sure to map ALL three distances
Chapter 5 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 5 - For parts a, b, and c, draw a diagram illustrating...Ch. 5 - 5.2 In a diploid species of plant, the genes for...Ch. 5 - A pure-breeding tall plant producing oval fruit as...Ch. 5 - 5.4 Genes E and H are syntenic in an experimental...Ch. 5 - In tomato plants, purple leaf color is controlled...Ch. 5 - 5.6 In Drosophila, the map positions of genes are...Ch. 5 - 5.7 Genes A, B, and C are linked on a chromosome...Ch. 5 - Gene G recombines with gene T at a frequency of...Ch. 5 - Genes A, B, C, D, and E are linked on a...Ch. 5 - Syntenic genes can assort independently. Explain...
Ch. 5 - The recombination frequency between linked genes...Ch. 5 - On the DrosophilaX chromosome, the dominant allele...Ch. 5 - Researchers cross a corn plant that is pure -...Ch. 5 - 5.14 syndrome is an autosomal disorder affecting...Ch. 5 - 5.15 Three dominant traits of corn seedlings,...Ch. 5 - 5.16 In a diploid plant species, an with the...Ch. 5 - Prob. 17PCh. 5 - The Rh blood group in humans is determined by a...Ch. 5 - 5.19 Genetic linkage mapping for a large number of...Ch. 5 - 20. Neurospora with the genotype form tetrads in...Ch. 5 -
Gene and gene are genetically linked. Answer...Ch. 5 -
T. H. Morgan’s data on eye color and wing form,...Ch. 5 - Prob. 23PCh. 5 -
The boss in your laboratory has just heard of a...Ch. 5 - In rabbits, chocolate-colored fur (w+) is dominant...Ch. 5 - Prob. 26PCh. 5 - 5.27 In tomatoes, the allele for tall plant height...Ch. 5 - 5.28 Neurofibromatosis is an autosomal dominant...Ch. 5 - A 2006 genetic study of a large American family...Ch. 5 - 5.30 A experiment examining potential genetic...Ch. 5 - 31. As part of their analysis of intragenic...Ch. 5 - In experiments published in 1918 that sought to...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- In a cross in Drosophila, a female heterozygous for the autosomallylinked genes a, b, c, d, and e (abcde/ + + + + +) was testcrossedwith a male homozygous for all recessive alleles (abcde/abcde).Even though the distance between each of the loci was at least3 map units, only four phenotypes were recovered, yielding thefollowing data: Phenotype No. of Flies+ + + + + 440a b c d e 460+ + + + e 48a b c d + 52 Total = 1000 Why are many expected crossover phenotypes missing? Can anyof these loci be mapped from the data given here? If so, determinemap distances.arrow_forwardThe A locus and the D locus are so tightly linked that norecombination is ever observed between them. If Ad/Ad is crossed with aD/aD and the F1 is intercrossed,what phenotypes will be seen in the F2 and in whatproportions?arrow_forwardIn the accompanying pedigree, the vertical lines stand for protan color blindness, and the horizontal lines stand for deutan color blindness. These are separate conditions causing different misperceptions of colors; each is determined by a separate gene.a. Does the pedigree show any evidence that the genes are linked? b. If there is linkage, does the pedigree show any evidence of crossing over? Explain your answers to parts a and b with the aid of the diagram. c. Can you calculate a value for the recombination between these genes? Is this recombination by independent assortment or by crossing over?(picture added)arrow_forward
- In a species of firefly, wide wings (W) are dominant to narrow wings (w) and graybodies (C) are dominant to brown bodies (c). A WwCc and wwcc fly were mated andproduced the following offspring: (in the picture attached) What is the recombination frequency for this cross (in percent)?arrow_forwardThe fruit fly, Drosophila melanogaster, a vestigial female fly is mated to a male that is scarlet eyes and bristled. Phenotypically wild type F1 female progeny were mated to fully homozygous (mutant) males, and the following progeny (of 1000 total) were observed (shown on table) a. Which gene is in the middle? b. What are the map distances between the three genes for this question? c. Calculate and show the work for coefficient of coincidence d. Calculate the interference. What does this mean and what does it tell you?arrow_forwardA Neurospora cross was made between a strain that carried the mating-type allele A and the mutant allele arg-1and another strain that carried the mating-type allele aand the wild-type allele for arg-1 (+). Four hundred linear octads were isolated, and they fell into the sevenclasses given in the table below. (For simplicity, they areshown as tetrads.)a. Deduce the linkage arrangement of the mating-typelocus and the arg-1 locus. Include the centromere orcentromeres on any map that you draw. Label all intervalsin map units.b. Diagram the meiotic divisions that led to class 6. Labelclearlyarrow_forward
- A series of three-point testcrosses is made to determine the genetic map order of seven linked allele pairs: A/a, B/b, G/g, H/h, Q/q, R/r, and Y/y.From each cross between a triply heterozygous parent listed below, two recombinant classes were noticed as the least frequent among all 8 progeny classes, and are listed at the right in the table. A. For each testcross write the genotype of the F1 heterozygous parent. F1 Parental Phenotype Least frequent F2 Phenotype 1.AHB&ahb AHb & ahB 2.RYh&ryH RYH & ryh 3.BhY&bHy Bhy & bHY 4.qYB&Qyb qYb & QyB 5.AbQ&aBq Abq & aBQ 6.ghR&GHr ghr & GHR B. Write the unified map order of these genes, showing your reasoning.arrow_forwardConsider two maize plants:a. Genotype C/cm ; Ac/Ac+, where cm is an unstableallele caused by a Ds insertionb. Genotype C/cm, where cm is an unstable allele causedby Ac insertionWhat phenotypes would be produced and in whatproportions when (1) each plant is crossed with a basepair-substitution mutant c/c and (2) the plant in part a iscrossed with the plant in part b? Assume that Ac and care unlinked, that the chromosome-breakage frequencyis negligible, and that mutant c /C is Ac+.arrow_forwardIn an autotetraploid Chinese primrose (Primula sinensis L.), the gene controlling stigma color is very near the centromere of the chromosome carrying it. The allele G for green stigma is dominant to g for red stigmas. A homozygous green autotetraploid strain is crossed with a homozygous red autotetraploid strain. a. What phenotypic ratio of green to red is expected if: i. The F1’s are intercrossed? ii. The F1’s are crossed with red plants b. If the G locus were 50 or more map units from the centromere, what types and proportions of gametes would the F1 be expected to produce? Derive the expected F2 phenotypic ratio.arrow_forward
- The drug ivacaftor has recently been developed totreat cystic fibrosis in children with the rare G551Dmutant allele of CFTR.a. Do you think that ivacaftor would be effective onlyin patients homozygous for the G551D mutation,or might it work as well in compound heterozygotes in which one copy of chromosome 7 hadG551D and the other copy a different allele ofCFTR, such as the more prevalent allele ΔF508?(The protein encoded by G551D folds up properlyand inserts into the cell membrane, but is inefficient in chloride ion transport. Ivacaftor increasesthe efficiency of G551D’s ion transport. TheΔF508 protein does not fold up properly and therefore does not get inserted into the cell membrane.)b. Why do you think ivacaftor would be more effectivein children than in older cystic fibrosis patients?c. The scientists who developed ivacaftor had a modelfor cystic fibrosis: a line of cells that grow in culture and that are homozygous for G551D. Thesecells accumulate mucus at their surfaces that…arrow_forwardIn autotetraploid Chinese primrose (Primula sinensis L.), the gene controlling stigma color is very near the centromere of the chromosome carrying it. The allele G for green stigma is dominant to g for red stigmas. A homozygous green autotetraploid strain is crossed with a homozygous red autotetraploid strain. 1. What phenotypic ratio of green to red is expected if: a. the Fl's are intercrossed? Show your solution. b. the Fl's are crossed with red plants? Show your solution. c. If the G locus were 50 or more map units from the centromere, what types and proportions of gametes would the Fl be expected to produce? Derive the expected F2 phenotypic ratio.arrow_forwardThe wild-type (W) Abraxas moth has large spots on its wings, but the lacticolor (L) form of this species has very small spots. Crosses were made between strains differing in this character, with the following results:Provide a clear genetic explanation of the results in these two crosses, showing the genotypes of all individual moths.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY