Genetic Analysis: An Integrated Approach (2nd Edition)
Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 5, Problem 31P

As part of their analysis of intragenic recombination, Melvin Green and Kathleen Green studied lozenge - eyed females with the mutation lz 46 on one X chromosome and the mutation lz g on the homologous X chromosome. The lz g - bearing X chromosome also carried recessive mutations for cut wing (ct) and vermilion - colored eye (v). These females were mated to cut wing males that had vermilion - colored, lozenge - shaped eyes. The chromosomes of these flies are depicted in the following drawing.

Chapter 5, Problem 31P, 31. As part of their analysis of intragenic recombination, Melvin Green and Kathleen Green studied

Diagram the recombination event within the lz gene and draw the resulting recombinant X chromosomes, illustrating the lz alleles and the flanking markers on each chromosome.

What are the phenotypes of progeny male flies carrying lz intragenic recombinants? (A double - mutant X chromosome carrying both lz g and lz 46 produces a compound lozenge eye that has a different appearance than either the lz g - or lz 46 - derived eye.)

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Given the distance between the orange eye color locus and the STRs, how frequent will you expect to get recombinant progeny with orange eyes? What would the probability of this marriage be producing children with orange eyes?
In a series of two-point mapping crosses involving five genes located on chromosome II in Drosophila, the following recombinant (single-crossover) frequencies were observed: pr–adp 29% pr–vg 13 pr–c 21 pr–b 6 adp–b 35 adp–c 8 adp–vg 16 vg–b 19 vg–c 8 c–b 27 (a) Given that the adp gene is near the end of chromosome II (locus 83), construct a map of these genes. (b) In another set of experiments, a sixth gene, d, was tested against b and pr: d–b 17% d–pr 23% Predict the results of two-point mapping between d and c, d and vg, and d and adp.
To determine the recombination frequency between body color and wing genes in flies, you perform several crosses where you cross an F1 having red body and smooth wings with a yellow-bodied, crinkle-winged fly. You get the following results. What is the distance between the genes for body color and wing surface in map units?

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Genetic Analysis: An Integrated Approach (2nd Edition)

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