As part of their analysis of intragenic recombination, Melvin Green and Kathleen Green studied lozenge
Diagram the recombination event within the lz gene and draw the resulting recombinant X chromosomes, illustrating the lz alleles and the flanking markers on each chromosome.
What are the
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Genetic Analysis: An Integrated Approach (2nd Edition)
- In a series of two-point map crosses involving five genes locatedon chromosome II in Drosophila, the following recombinant (single- crossover) frequencies were observed:pr–adp 29pr–vg 13pr–c 21pr–b 6adp–b 35adp–c 8adp–vg 16vg–b 19vg–c 8c–b 27 In another set of experiments, a sixth gene (d) was testedagainst b and pr, and the results were d - b = 17% andd - pr = 23%. Predict the results of two-point mapsbetween d and c, d and vg, and d and adp.arrow_forwardIndividuals of genotype AaBb were mated to individuals of genotype aabb. One thousand offspring were counted, with the following results: 474 Aabb, 480 aaBb, 20 AaBb, and 26 aabb. What type of cross is it? Are these loci linked? What are the two parental classes and the two recombinant classes of offspring? What is the percentage of recombination between these two loci? How many map units apart are they?arrow_forwardGiven the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the phenotype of this individual be?arrow_forward
- A proband female with an unidentified disease seeks the advice of a genetic counselor before starting a family. Based on the following data, the counselor constructs a pedigree encompassing three generations: (1) The maternal grandfather of the proband has the disease. (2) The mother of the proband is unaffected and is the youngest of five children, the three oldest being male. (3) The proband has an affected older sister, but the youngest siblings are unaffected twins (boy and girl). (4) All the individuals who have the disease have been revealed. Duplicate the counselors featarrow_forwardWhat is the distance between the orange eye color locus and the STRs, how frequent will you expect to get recombinant progeny with orange eyes? What would the probability of this marriage be producing children with orange eyes?arrow_forwardFor this particular family, what is the recombination rate between the D17S74 marker and the breast cancer gene? Lets say that at age 45 the third granddaughter III-3, is diagnosed with breast cancer. Now recalculate the recombination rate between the marker locus D17S74 and the breast cancer gene? Use only the 5 women in your analysis:the two daugthers in generation II and the three granddaughters in generation IIarrow_forward
- An individual is heterozygous for a reciprocal translocation, with the following chromosomes: A • B C D E F A • B C V W X R ST • U D E F R ST • U V W X Q. Explain why the fertility of this individual is likely to be less than the fertility of an individual without a translocation.arrow_forwardIn a diploid plant species, an F1 with the genotype Mm Rr Ss is test crossed to a pure breeding recessive plant with the genotype mm rr ss. The offspring genotypes are as follows: Genotype Number Mm Rr Ss 687 Mm Rr ss 5 Mm rr Ss 68 Mm rr ss 196 mm Rr Ss 185 mm Rr ss 72 mm rr Ss 8 mm rr ss 679 Total 1900 1. Why is the recombination frequency for the outside pair of genes not equal to the sum of the recombination between the adjacent gene pairs?arrow_forwardThree autosomal recessive mutations in yeast, all producing the same phenotype (m1, m2, and m3), are subjected to complementation analysis. Of the results shown below, which, if any, are alleles of one another? Predict the results of the cross that is not shown—that is, m2 * m3. Cross 1: m1 * m24 F1: all wild-type progeny Cross 2: m1 * m34 F1: all mutant progenyarrow_forward
- In a series of two-point map crosses involving five genes locatedon chromosome II in Drosophila, the following recombinant (single-crossover) frequencies were observed:pr–adp 29pr–vg 13pr–c 21pr–b 6adp–b 35adp–c 8adp–vg 16vg–b 19vg–c 8c–b 27 If the adp gene is present near the end of chromosome II(locus 83), construct a map of these genes.arrow_forwardIn a particular organism, the A locus and the D locus are so tightly linked that no crossing over is ever observed between them. If an AADD individual is crossed to an aadd individual, what types of gametes will their double-heterozygote F1 offspring produce and in what proportions? Group of answer choices 25% parental and 75% recombinant gametes 75% parental and 25% recombinant gametes 100% parental and 0% recombinant gametes 50% parental and 50% recombinant gametes 0% parental and 100% recombinant gametesarrow_forwardIn the experiment of Figure shown, Stern followed the inheritancepattern in which females carried two abnormal X chromosomesto correlate genetic recombination with the physical exchange ofchromosome pieces. Is it necessary to use a strain carrying twoabnormal chromosomes, or could he have used a strain in whichfemales carried one normal X chromosome and one abnormal Xchromosome with a deletion at one end and an extra piece of the Ychromosome at the other end?arrow_forward
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