Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 5, Problem 23P
In Drosophila, the recessive allele mb of one gene causes missing bristles, the recessive allele e of a second gene causes ebony body color, and the recessive allele k of a third gene causes kidney-shaped eyes. (Dominant wild-type alleles of all three genes are indicated with a + superscript.) The three different P generation crosses in the table that follows were conducted, and then the resultant F females from each cross were testcrossed to males that were homozygous for the recessive alleles of both genes in question. The
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The recessive allele s causes Drosophila to have small wings, and the s+ allele causes normal wings. This gene is known to be X linked. If a small-winged male is crossed with a homozygous wild-type female, what ratio of normal to small-winged flies can be expected in each sex in the F1? If F1 flies are intercrossed, what F2 progeny ratios are expected? What progeny ratios are predicted if F1 females are backcrossed with their father?
In Drosophila, a cross was made between a yellow-bodied male with vestigial wings and a wild-type (WT) female(brown body and normal wings). The F1 generation consisted of WT males and WT females. The F1 males and females were crossed, and the F2 progeny consisted of 16 yellow males with vestigial wings, 48 yellow males with WT wings, 15 brown males with vestigial wings, 49 WT males, 31 brown females with vestigial wings, and 97 WT females. Based on these results, explain the inheritance of the two genes (i.e. autosomal or sex-linked, dominant or recessive).
In Drosophila, white eyes (w) are recessive to red eyes (w+) at one locus and black body (b) is recessive to gray body (b+). A homozygous white eyes, gray bodied female is crossed with a homozygous red eyes, black bodied male to produce the F1 progeny. The F1 progeny are testcrossed and produce the following progeny:
White eyes, black body: 212
White eyes, gray body: 288
Red eyes, black body: 308
Red eyes, gray body: 192
Does the evidence indicate that w and b loci are linked? Explain why or why not?
If they are linked, what is the map distance between the two loci? If they are not linked, what is the map distance between the two loci? If they are linked, are the allels in the F1 in coupling or repulsion? How do you know?
Draw the genotypes of all individuals described in the problem (original parents, F1, testcross, and F2 progeny) using the appropriate notation.
Chapter 5 Solutions
Genetics: From Genes to Genomes
Ch. 5 - Choose the phrase from the right column that best...Ch. 5 - a. A Drosophila male from a true-breeding stock...Ch. 5 - Prob. 3PCh. 5 - The Punnett square in Fig. 5.4 shows how Mendels...Ch. 5 - In mice, the dominant allele Gs of the X-linked...Ch. 5 - In Drosophila, males from a true-breeding stock...Ch. 5 - If the a and b loci are 20 m.u. apart in humans...Ch. 5 - CCDD and ccdd individuals were crossed to each...Ch. 5 - In mice, the autosomal locus coding for the...Ch. 5 - In a particular human family, John and his mother...
Ch. 5 - Albino rabbits lacking pigment are homozygous for...Ch. 5 - In corn, the allele A allows the deposition of...Ch. 5 - If the a and b loci are 40 cM apart and an AA BB...Ch. 5 - Write the number of different kinds of phenotypes,...Ch. 5 - A DNA variant has been found linked to a rare...Ch. 5 - Figure 5.7a shows chromosomes during prophase of...Ch. 5 - Figure 5.7b shows bivalents in mouse primary...Ch. 5 - Cinnabar eyes cn and reduced bristles rd are...Ch. 5 - In Drosophila, the autosomal recessive dp allele...Ch. 5 - From a series of two-point crosses, the following...Ch. 5 - Map distances were determined for four different...Ch. 5 - In the tubular flowers of foxgloves, wild-type...Ch. 5 - In Drosophila, the recessive allele mb of one gene...Ch. 5 - A snapdragon with pink petals, black anthers, and...Ch. 5 - In Drosophila, three autosomal genes have the...Ch. 5 - Drosophila females heterozygous for each of three...Ch. 5 - Male Drosophila expressing the autosomal recessive...Ch. 5 - a. In Drosophila, crosses between F1 heterozygotes...Ch. 5 - A true-breeding strain of Virginia tobacco has...Ch. 5 - Prob. 30PCh. 5 - The following list of four Drosophila mutations...Ch. 5 - Do the data that Mendel obtained fit his...Ch. 5 - Two genes control color in corn snakes as follows:...Ch. 5 - A mouse from a true-breeding population with...Ch. 5 - Neurospora of genotype a c are crossed with...Ch. 5 - A cross was performed between one haploid strain...Ch. 5 - Prob. 40PCh. 5 - Prob. 41PCh. 5 - Indicate the percentage of tetrads that would have...Ch. 5 - Prob. 43PCh. 5 - This problem leads you through the derivation of a...Ch. 5 - a. In ordered tetrad analysis, what is the maximum...Ch. 5 - Prob. 46PCh. 5 - A single yeast cell placed on a solid agar will...Ch. 5 - Figure 5.29 shows mitotic recombination leading to...Ch. 5 - A diploid strain of yeast has a wild-type...Ch. 5 - In Drosophila, the yellow y gene is near the...Ch. 5 - Neurofibromas are tumors of the skin that can...Ch. 5 - Two important methods for understanding the...
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