Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 5, Problem 2P
| a. | A Drosophila male from a true-breeding stock with scabrous eyes was mated with a female from a true-breeding stock with javelin bristles. Both scabrous eyes and javelin bristles are autosomal recessive traits. The F1 progeny all had normal eyes and bristles. F1 females from this cross were mated with males with both scabrous eyes and javelin bristles. Write all the possible |
| b. | The cross above yielded the following progeny: 77 scabrous eyes and normal bristles; 76 wild type (normal eyes and bristles); 74 normal eyes and javelin bristles; and 73 scabrous eyes and javelin bristles. Are the genes governing these traits likely to be linked, or do they instead assort independently? Why? |
| c. | Suppose you mated the F1 females from the cross in part (a) to wild-type males. Why would this cross fail to inform you whether the two genes are linked? |
| d. | Suppose you mated females from the true-breeding stock with javelin bristles to males with scabrous eyes and javelin bristles. Why would this cross fail to inform you whether the two genes are linked? |
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Consider a cross between a Brown furred dog and a Yellow furred dog. All the puppies born from these parents are yellow furred. Crossing the F1 yellow furred sons and F1 yellow furred daughters produces a 3:1 ratio of yellow furred dogs (3) to brown-furred dogs (1) in the F2 generation.
True or False: this tells you that brown fur color in this dog species is inherited in an autosomal recessive manner.
is it true or false?
In Drosophila, the sepia mutation (se, chromosome 3, position 26) results in dark brown eyes, while cinnabar (cn, chromosome 2, position 57.5) results in bright orange-red eyes. True breeding, wild type females are mated with true breeding males homozygous recessive for both traits.
Using Drosophila notation, diagram the P1 and F1 crosses.
P1 F1
Fill in the chart with phenotypic ratios that would be expected in the F2 generation. Use the space provided to show your work.
Phenotype
Females
Males
Overall (♀and ♂)
=1 =1
Consider a situation where you have a parental cross with the mother and father phenotypes listed below. Remember that the genotype for the wild-type parent is always homozygous.
The counts of the F1 offspring are listed in Table 1. Two randomly selected individuals are selected and mated to produce a set of F2 individuals. If you test the F2 counts to determine whether they are consistent with an autosomal dominant mode of inheritance, what is your decision? Use a 0.05 significance level.
PARENTAL CROSS
Parental cross: Mother with disease phenotype, Father with wild-type phenotype.
Table 1. F1 DATA
Gender
Phenotype
Disease
Wild-type
Male
0
23
Female
0
34
Table 2. F2 DATA
Gender
Phenotype
Disease
Wild-type
Male
7
25
Female
0
25
A)Do not reject the null hypothesis that the F2 data are consistent with an autosomal dominant mode of inheritance; chi-square goodness of fit test statistic value is between 0 and 1.
B)Reject the null…
Chapter 5 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 5 - Choose the phrase from the right column that best...Ch. 5 - a. A Drosophila male from a true-breeding stock...Ch. 5 - Prob. 3PCh. 5 - The Punnett square in Fig. 5.4 on p. 131 shows how...Ch. 5 - In mice, the dominant allele Gs of the X-linked...Ch. 5 - In Drosophila, males from a true-breeding stock...Ch. 5 - If the a and b loci are 20 m.u. apart in humans...Ch. 5 - CCDD and ccdd individuals were crossed to each...Ch. 5 - In mice, the autosomal locus coding for the...Ch. 5 - In a particular human family, John and his mother...
Ch. 5 - Albino rabbits lacking pigment are homozygous for...Ch. 5 - In corn, the allele A allows the deposition of...Ch. 5 - If the a and b loci are 40 cM apart and an AA BB...Ch. 5 - Write the number of different kinds of phenotypes,...Ch. 5 - A DNA variant has been found linked to a rare...Ch. 5 - Figure 5.7a on p. 134 shows chromosomes during...Ch. 5 - Figure 5.7b shows bivalents in mouse primary...Ch. 5 - Cinnabar eyes cn and reduced bristles rd are...Ch. 5 - In Drosophila, the autosomal recessive dp allele...Ch. 5 - From a series of two-point crosses, the following...Ch. 5 - Map distances were determined for four different...Ch. 5 - In the tubular flowers of foxgloves, wild-type...Ch. 5 - In Drosophila, the recessive allele mb of one gene...Ch. 5 - A snapdragon with pink petals, black anthers, and...Ch. 5 - In Drosophila, three autosomal genes have the...Ch. 5 - Drosophila females heterozygous for each of three...Ch. 5 - Male Drosophila expressing the autosomal recessive...Ch. 5 - a. In Drosophila, crosses between F1 heterozygotes...Ch. 5 - A true-breeding strain of Virginia tobacco has...Ch. 5 - Prob. 30PCh. 5 - The following list of four Drosophila mutations...Ch. 5 - Do the data that Mendel obtained fit his...Ch. 5 - Two genes control color in corn snakes as follows:...Ch. 5 - A mouse from a true-breeding population with...Ch. 5 - Neurospora of genotype a c are crossed with...Ch. 5 - A cross was performed between one haploid strain...Ch. 5 - A cross was performed between a yeast strain that...Ch. 5 - Two crosses were made in Neurospora involving the...Ch. 5 - Indicate the percentage of tetrads that would have...Ch. 5 - Prob. 42PCh. 5 - Prob. 43PCh. 5 - Prob. 44PCh. 5 - a. In ordered tetrad analysis, what is the maximum...Ch. 5 - A research group has selected three independent...Ch. 5 - A single yeast cell placed on a solid agar will...Ch. 5 - Prob. 48PCh. 5 - In Drosophila, the yellow y gene is near the end...Ch. 5 - Neurofibromas are tumors of the skin that can...Ch. 5 - Two important methods for understanding the...
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