Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 5, Problem 45P
a. | In ordered tetrad analysis, what is the maximum RF that you could observe between a gene and its centromere? (Hint: What RF would you observe between a gene and the centromere of the chromosome on wich it resides if the gene were distant enough from the centromere so that there was at least one crossover, and often more than one crossover, occurs between them in every meiosis?) |
b. | Can a gene and its centromere be unlinked? Explain. |
c. | Suppose in an ordered tetrad analysis you observe an RF of 30% between a gene and the centromere. Given your answer to part (a), do think that 30 m.u. is an accurate estimate of the distance between the gene and the centromere? |
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An individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B • C D E F G A B • C D V W X R S • T U E F G R S • T U V W X a. Draw the pairing arrangement of these chromosomes in prophase I of meiosis. b. Diagram the alternate, adjacent-1, and adjacent-2 segregation patterns in anaphase I of meiosis. c. Give the products that result from alternate, adjacent-1, and adjacent-2 segregation.
We have discussed meiosis in yeast. One ascus e one melotic event.
Two haploid yeast strains are crossed together, one wild type, the other mutant for 2 linked genes. The resulting diploid strain
undergoes melosis eventually (=many meiotic events > many asci).
A. What will the results be if the 2 genes are very far away from each other (certainly more than 50 map units)?
B. What will the results be if the two genes are right next to each other, "no distance at all, zero distance"?
(Explain your answers).
Results here are patterns of asci and their percentages. Like for example "50% tetratypes, 0% ditypes", etc. If you forgot what a
ditype or a tetratype is, you can illustrate them like that.
a. The 2 daughter cells produced from meiosis I are IDENTICAL/UNIQUE (choose one)
compared to each other. Explain how you determined the cells were genetically identical or
unique.
b. The daughter cells are HAPLOID / DIPLOID (choose one) because homologous pairs ARE/ARE
NOT (choose one) present in the same cell. The chromosomes in each daughter cell are
DUPLICATED/ UNDUPLICATED (choose one).
essibility: Investigate
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Chapter 5 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 5 - Choose the phrase from the right column that best...Ch. 5 - a. A Drosophila male from a true-breeding stock...Ch. 5 - Prob. 3PCh. 5 - The Punnett square in Fig. 5.4 on p. 131 shows how...Ch. 5 - In mice, the dominant allele Gs of the X-linked...Ch. 5 - In Drosophila, males from a true-breeding stock...Ch. 5 - If the a and b loci are 20 m.u. apart in humans...Ch. 5 - CCDD and ccdd individuals were crossed to each...Ch. 5 - In mice, the autosomal locus coding for the...Ch. 5 - In a particular human family, John and his mother...
Ch. 5 - Albino rabbits lacking pigment are homozygous for...Ch. 5 - In corn, the allele A allows the deposition of...Ch. 5 - If the a and b loci are 40 cM apart and an AA BB...Ch. 5 - Write the number of different kinds of phenotypes,...Ch. 5 - A DNA variant has been found linked to a rare...Ch. 5 - Figure 5.7a on p. 134 shows chromosomes during...Ch. 5 - Figure 5.7b shows bivalents in mouse primary...Ch. 5 - Cinnabar eyes cn and reduced bristles rd are...Ch. 5 - In Drosophila, the autosomal recessive dp allele...Ch. 5 - From a series of two-point crosses, the following...Ch. 5 - Map distances were determined for four different...Ch. 5 - In the tubular flowers of foxgloves, wild-type...Ch. 5 - In Drosophila, the recessive allele mb of one gene...Ch. 5 - A snapdragon with pink petals, black anthers, and...Ch. 5 - In Drosophila, three autosomal genes have the...Ch. 5 - Drosophila females heterozygous for each of three...Ch. 5 - Male Drosophila expressing the autosomal recessive...Ch. 5 - a. In Drosophila, crosses between F1 heterozygotes...Ch. 5 - A true-breeding strain of Virginia tobacco has...Ch. 5 - Prob. 30PCh. 5 - The following list of four Drosophila mutations...Ch. 5 - Do the data that Mendel obtained fit his...Ch. 5 - Two genes control color in corn snakes as follows:...Ch. 5 - A mouse from a true-breeding population with...Ch. 5 - Neurospora of genotype a c are crossed with...Ch. 5 - A cross was performed between one haploid strain...Ch. 5 - A cross was performed between a yeast strain that...Ch. 5 - Two crosses were made in Neurospora involving the...Ch. 5 - Indicate the percentage of tetrads that would have...Ch. 5 - Prob. 42PCh. 5 - Prob. 43PCh. 5 - Prob. 44PCh. 5 - a. In ordered tetrad analysis, what is the maximum...Ch. 5 - A research group has selected three independent...Ch. 5 - A single yeast cell placed on a solid agar will...Ch. 5 - Prob. 48PCh. 5 - In Drosophila, the yellow y gene is near the end...Ch. 5 - Neurofibromas are tumors of the skin that can...Ch. 5 - Two important methods for understanding the...
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