Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
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Chapter 7, Problem 26P
| a. | In Figure 7.22b, what can you say about the phenotype(s) of the progeny indicated by a +? Explain. |
| b. | What about the |
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Chapter 7 Solutions
Genetics: From Genes to Genomes
Ch. 7 - The following is a list of mutational changes. For...Ch. 7 - What explanations can account for the following...Ch. 7 - The DNA sequence of one strand of a gene from...Ch. 7 - Among mammals, measurements of the rate of...Ch. 7 - Over a period of several years, a large hospital...Ch. 7 - Suppose you wanted to study genes controlling the...Ch. 7 - In a genetics lab, Kim and Maria infected a sample...Ch. 7 - The results of the fluctuation test Fig. 7.5 were...Ch. 7 - The following pedigree shows the inheritance of a...Ch. 7 - Autism is a neurological disorder thought to be...
Ch. 7 - Like the yellow Labrador retrievers featured in...Ch. 7 - Remember that Balancer chromosomes prevent the...Ch. 7 - Figure 7.14 shows examples of base substitutions...Ch. 7 - Figure 7.14a shows the mutagen 5-bromouracil 5-BU,...Ch. 7 - So-called two-way mutagens can induce both a...Ch. 7 - In 1967, J. B. Jenkins treated wild-type male...Ch. 7 - When a particular mutagen identified by the Ames...Ch. 7 - Prob. 18PCh. 7 - The Ames test uses the reversion rate His- to His...Ch. 7 - The mutant FMR-1 allele that causes fragile X...Ch. 7 - The physicist Stephen Hawking, famous for his...Ch. 7 - Aflatoxin B1 is a highly mutagenic and...Ch. 7 - In human DNA, 70 of cytosine residues that are...Ch. 7 - Bromodeoxyuridine BrdU is a synthetic nucleoside...Ch. 7 - Albinism in animals is caused by recessive...Ch. 7 - a. In Figure 7.22b, what can you say about the...Ch. 7 - Imagine that you caught a female albino mouse in...Ch. 7 - Plant breeders studying genes influencing leaf...Ch. 7 - In humans, albinism is normally inherited in an...Ch. 7 - a. Seymour Benzers fine structure analysis of the...Ch. 7 - a. You have a test tube containing 5 ml of a...Ch. 7 - Prob. 32PCh. 7 - The rosy ry gene of Drosophila encodes an enzyme...Ch. 7 - Nine rII- mutants of bacteriophage T4 were used in...Ch. 7 - In a haploid yeast strain, eight recessive...Ch. 7 - In Problem 24, you learned that Bloom syndrome is...Ch. 7 - The pathway for arginine biosynthesis in...Ch. 7 - In corn snakes, the wild-type color is brown. One...Ch. 7 - In a certain species of flowering plants with a...Ch. 7 - The intermediates A, B, C, D, E, and F all occur...Ch. 7 - In each of the following cross schemes, two...Ch. 7 - Prob. 42PCh. 7 - The following complementing E. coli mutants were...Ch. 7 - In 1952, an article in the British Medical Journal...Ch. 7 - Mutations in an autosomal gene in humans cause a...Ch. 7 - Antibodies were made that recognize six proteins...Ch. 7 - Prob. 47PCh. 7 - Prob. 48PCh. 7 - In addition to the predominant adult hemoglobin,...Ch. 7 - Most mammals, including New World primates such as...Ch. 7 - Humans are normally trichromats; we have three...
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- Could the pedigree in Figure 2-31 be explained as an autosomal dominant disorder? Explain.arrow_forward. The pedigree below was obtained for a rare kidney disease.a. Deduce the inheritance of this condition, stating your reasons. b. If persons 1 and 2 marry, what is the probability that their first child will have the kidney disease?arrow_forwarda. Among the progeny of a self-fertilized semisterilecorn plant heterozygous for a reciprocal translocation, what ratio do you expect for progeny plantswith normal fertility versus those showing semisterility? In this problem, ignore the rare gametesproduced by adjacent-2 segregation.b. Among the progeny of a particular self-fertilizedsemisterile corn plant heterozygous for a reciprocaltranslocation, the ratio of fertile to semisterileplants was 1:4. How can you explain this deviationfrom your answer to part (a)?arrow_forward
- . Male house cats are either black or orange; females areblack, orange, or calico.a. If these coat-color phenotypes are governed by a sexlinked gene, how can these observations be explained?b. Using appropriate symbols, determine the phenotypes expected in the progeny of a cross between anorange female and a black male.c. Half the females produced by a certain kind of matingare calico, and half are black; half the males are orange,and half are black. What colors are the parental malesand females in this kind of mating?d. Another kind of mating produces progeny in thefollowing proportions: one-fourth orange males, onefourth orange females, one-fourth black males, and onefourth calico females. What colors are the parental malesand females in this kind of mating?arrow_forwardThree autosomal recessive mutations in yeast, all producing the same phenotype (m1, m2, and m3), are subjected to complementation analysis. Of the results shown below, which, if any, are alleles of one another? Predict the results of the cross that is not shown—that is, m2 * m3. Cross 1: m1 * m24 F1: all wild-type progeny Cross 2: m1 * m34 F1: all mutant progenyarrow_forwardIn the accompanying pedigree, the vertical lines stand for protan color blindness, and the horizontal lines stand for deutan color blindness. These are separate conditions causing different misperceptions of colors; each is determined by a separate gene.a. Does the pedigree show any evidence that the genes are linked? b. If there is linkage, does the pedigree show any evidence of crossing over? Explain your answers to parts a and b with the aid of the diagram. c. Can you calculate a value for the recombination between these genes? Is this recombination by independent assortment or by crossing over?(picture added)arrow_forward
- The pedigree below shows that inheritance of a disease that is caused by a late onset, dominant, autosomal mutation that is rare, but only 50% penetrant. The gene that is mutated in the disease is linked at a distance of 10 cm to a microsatellite marker that has alleles numbered 1, 2, and 3. The marker alleles detected in each individual are indicated below. What is the probability that individual A will develop the disease? Explain using an illustration of this occurs.arrow_forwardGiven the distance between the orange eye color locus and the STRs, how frequent will you expect to get recombinant progeny with orange eyes? What would the probability of this marriage be producing children with orange eyes?arrow_forwardThis is a pedigree for a dominant trait caused by gene A in humans. Shaded symbols show individuals affected with the trait; non-shaded individuals are normal (aa). Among the progeny arising from the marriage of individual III-1, what proportion would be expected to show the trait? Among the progeny arising from the marriage of individual III-6, what proportion would be expected to show the trait?arrow_forward
- In a two factor cross, the longest possible map distance is 50 map units. Explain why this is true. How then can genetic maps show two genes that are 70 map units or more apart?arrow_forwardGiven the following pedigree (note that C7C, M4C, N2X, H6C, G9X, J1C, B8X, and P2X are the names of animals): arrow_forwardA rare blinding disease that has a relation to dengenerative factors is partially penetrant. In the following pedigrees for two families, the affected symptomatic individuals (black circles and squares) have been diagnosed with this disease due to the mutation in mitochondrial DNA m.14484T>C. If III.4 is homoplasmic for m.14484T>C in hair, blood, urine and other tissues examined. What will occur with IV.7 then?arrow_forward
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