Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 11, Problem 15QP
Summary Introduction
To explain: The working principle of the anticipation theory.
Introduction: Trinucleotide repeats are the sequences of three
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Chapter 11 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 11.4 - Consumer products including bandages, cotton...Ch. 11.4 - Prob. 2EGCh. 11 - Prob. 1CSCh. 11 - Prob. 2CSCh. 11 - Prob. 3CSCh. 11 - Prob. 1QPCh. 11 - Achondroplasia is an autosomal dominant form of...Ch. 11 - Why is it almost impossible to directly measure...Ch. 11 - What are the factors that influence the mutation...Ch. 11 - Achondroplasia is a rare dominant autosomal defect...
Ch. 11 - Although it is well known that X-rays cause...Ch. 11 - Prob. 7QPCh. 11 - Bruce Ames and his colleagues have pointed out...Ch. 11 - Define and compare the following types of...Ch. 11 - If the coding region of a gene (the exons)...Ch. 11 - Two types of mutations discussed in this chapter...Ch. 11 - Prob. 12QPCh. 11 - A frameshift mutation is caused by a: a....Ch. 11 - In the gene-coding sequence shown here, which of...Ch. 11 - Prob. 15QPCh. 11 - Familial retinoblastoma, a rare autosomal dominant...Ch. 11 - Tay-Sachs disease is an autosomal recessive...Ch. 11 - Replication involves a period of time during which...Ch. 11 - Our bodies are not defenseless against mutagens...Ch. 11 - The cystic fibrosis gene encodes a chloride...
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- The diagram to the right shows how tiles can be put together in different ways. How does this example relate to the role of DNA as the universal genetic material in organisms?arrow_forwardSome populations change noticeably in form within a hundred years. If only one gene in every 200,000 mutates and if most mutations are harmful, how is such change possible?arrow_forwardThe continuity of life is based on heritable information in the form of DNA, and structure and function are correlated at all levels of biological organization. In a short essay (100−150 words), describe how the structure of DNA is correlated with its role as the molecular basis of inheritance.arrow_forward
- Describe five different scenarios where a change in DNA sequence would result in a phenotypic change at the organismal (human) level.arrow_forwardMammals and prokaryotes use DNA as the molecule of heredity. What does this imply?arrow_forwardConsider a recessive condition where 40% of the affected individuals pass away by the age of 10 but those that survive to adulthood are just as likely to have children as the general population. What must the new mutation rate be if the incidence of the disorder is 1/10,000 to maintain a consistent incidence across generations? Answer format: Fraction - #/#arrow_forward
- if we have two or three repeats in our dna sequence, what happens to the de bruijn grapharrow_forwardComment on the utility of variability in number of tamndem repeats during DNA fingerprintingds?arrow_forwardUsing sickle cell as an example, give a detailed description of how the effects of a base substitution can be traced from DNA level to the level of the whole organism.arrow_forward
- Explain how genetic rearrangement creates a diverse set ofantibodies in mammals.arrow_forwardGiven our knowledge of genome sizes in different organisms, would you predict that Homo sapiens or the two-toed salamander (Amphiuma means) has the larger genome?arrow_forwardSuppose researchers learn that a particular congenital disease is caused by synthesis of a protein coded by a mutated gene. Describe a way in which recombinant DNA technology might be used to prevent translation of the protein.arrow_forward
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