Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Textbook Question
Chapter 11, Problem 13QP
A frameshift mutation is caused by a:
- a.
nucleotide substitution - b. three-base insertion
- c. premature stop codon
- d. one-base insertion
- e. two-base deletion
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The change of a UAC codon (Tyr) to a UAU codon (Tyr) is an example of a:
A.
missense mutation
B.
silent mutation
C.
frameshift mutation
D.
nonsense mutation
A mutation occurs that alters the third base in an mRNA codon from a C to a G. This mutation is most likely a
A.
frameshift mutation
B.
missense mutation
C.
nonsense mutation
D.
silent mutation
Missense mutations
a
create premature stop codons
b
cause no change in a gene product
c
change the amino acid sequence of a polypeptide
d
none of the above
Chapter 11 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 11.4 - Consumer products including bandages, cotton...Ch. 11.4 - Prob. 2EGCh. 11 - Prob. 1CSCh. 11 - Prob. 2CSCh. 11 - Prob. 3CSCh. 11 - Prob. 1QPCh. 11 - Achondroplasia is an autosomal dominant form of...Ch. 11 - Why is it almost impossible to directly measure...Ch. 11 - What are the factors that influence the mutation...Ch. 11 - Achondroplasia is a rare dominant autosomal defect...
Ch. 11 - Although it is well known that X-rays cause...Ch. 11 - Prob. 7QPCh. 11 - Bruce Ames and his colleagues have pointed out...Ch. 11 - Define and compare the following types of...Ch. 11 - If the coding region of a gene (the exons)...Ch. 11 - Two types of mutations discussed in this chapter...Ch. 11 - Prob. 12QPCh. 11 - A frameshift mutation is caused by a: a....Ch. 11 - In the gene-coding sequence shown here, which of...Ch. 11 - Prob. 15QPCh. 11 - Familial retinoblastoma, a rare autosomal dominant...Ch. 11 - Tay-Sachs disease is an autosomal recessive...Ch. 11 - Replication involves a period of time during which...Ch. 11 - Our bodies are not defenseless against mutagens...Ch. 11 - The cystic fibrosis gene encodes a chloride...
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- A SNV mutation that results in an early stop codon is called: A. silent mutation B. silencing mutation C. missense mutation D. nonsense mutation E. frameshift mutationarrow_forwardA mutation changes a codon that specifies tyrosine into a stopcodon. This type of mutation is aa. missense mutation.b. nonsense mutation.c. frameshift mutation.d. neutral mutation.arrow_forward_______ are removed from new mRNAs. a. Introns c. Poly-A tails b. Exons d. Amino acidsarrow_forward
- Portions of eukaryotic mRNA sequence that are removed during RNA processing are . a. exons b. caps c. poly-A tails d. intronsarrow_forwardWhich of the following mutations would be most likely to havea harmful effect on an organism?(A) a deletion of three nucleotides near the middle of a gene(B) a single nucleotide deletion in the middle of an intron(C) a single nucleotide deletion near the end of the codingsequence(D) a single nucleotide insertion downstream of, and close to,the start of the coding sequencearrow_forwardA mutation caused by a base deamination or a tautomerization is called a a. silent mutation b. transition mutation c. nonsense mutation d. missense mutationarrow_forward
- The original DNA base sequence is 5’-AGCGTTACCGT-3’; a mutation in the DNA strand results in the base sequence 5’-AGGCGTTACCGT-3’. What can you conclude about the mutation? A. It is a frameshift mutation. B. It is a silent mutation. C. It is a deleterious mutation. D. It may result in a single amino acid change in the protein being coded for by this base sequence.arrow_forwardA SNV mutation that results in no change in the amino acid sequence is called: A. silent mutation B. silencing mutation C. missense mutation D. nonsense mutation E. frameshift mutationarrow_forwardThe Kozak rules determine a. the choice of the start codon in complex eukaryotes. b. the choice of the start codon in bacteria. c. the site in the mRNA where translation ends. d. how fast the mRNA is translated.arrow_forward
- What type of mutation causes the "mutant" variety of the PTC gene? a A point mutation which lead to a nonsense mutation b A addition mutation which lead to a frameshift c A substitution mutation which lead to a missense mutation d A deletion mutation which lead to a SNP mutationarrow_forwardTranslation of the dna sequence AAGCTGGGA would result in: A) a DNA strand with the base sequence TTCGACCCT B) an mRNA strand with the sequence TTCGACCCT C) a sequence of three amino acids linked by peptide bonds D) an mRNA strand with the sequence UUGCACCCUarrow_forwardWhich of the following results in the same amino acid in its protein sequence? a. missense mutation b. sense mutation c. nonsense mutation d. antisense mutationarrow_forward
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