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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 11, Problem 3QP
Textbook Problem
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Why is it almost impossible to directly measure the mutation rates in autosomal recessive alleles?

Summary Introduction

To explain: The reason why it is impossible to measure the mutation rate of autosomal recessive alleles directly.

Introduction: Alleles are of two types, which are dominant alleles and recessive alleles. Dominant alleles are expressed in all conditions whether it is homozygous or heterozygous whereas recessive alleles are only expressed in homozygous condition. In heterozygous condition, its expression is masked by a dominant allele.

Explanation of Solution

Autosomal recessive alleles are expressed only in homozygous condition. If they are in heterozygous condition, they are not expressed and can be transferred from one generation to the other without being noticed. The direct measurement of mutation rate depends on the estimation...

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