Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 18, Problem 10RQ
Summary Introduction
To review:
Definition of the following terminologies:
a. Promoter
b. Consensus sequence
c. Operon
d. Chromatin remodeling complex
e. General transcription factors
Introduction:
DNA (deoxyribonucleic acid) replicates itself inside the cell through the process of replication. Further, the DNA transcribes the mRNA (messenger ribonucleic acid) through the process of transcription. The genome has several genes, some of which are actively transcribed all the time, while some are transcribed according to the cellular needs. Thus, the process of transcription is highly organized and regulated with the help of several elements and enzymes.
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Question 2:
Part a: Complete the table describing different components of intron removal from mRNA. Nu:, X and Y refer to B-type chemistry shown on the previous page. (YELLOW table shown)
Part b: Complete the table describing different components of group I self-splicing intron removal from 26S rRNA in Tetrahymena. (BLUE table shown)
Part c: Draw the intron with an all atom structure for Branchpoint A after intron removal from mRNA
Part d: Draw the Group I self-splicing intron with an all atom structure for the Guanosine cofactor after intron removal from 26S rRNA in Tetrahymena.
Question 14
A large RNA–protein complex responsible for RNA splicing is called:
Question 14 options:
Spliceosome
Splicing complex
Exon-intron processor
Transcription complex
Question 15
Shortly after transcriptional initiation by RNA polymerase II, a methylated nucleoside (7-methylguanosine, m7G) is added and linked by a 5′–5′ phosphodiester bond to the first 5′ nucleotide, What is this process called?
Question 15 options:
3' Capping
5' Capping
Polyadenylation
Splicing
Question 16
During polyadenylation, the RNA is cleaved at a specific site. The site is:
Question 16 options:
15–30 nucleotides downstream of the AAUAAA sequence
15–30 nucleotides upstream of the AAUAAA sequence
at AAUAA sequence
At…
what state will the prokaryotic repressor protein take in the place of lactose
Chapter 18 Solutions
Biochemistry: The Molecular Basis of Life
Ch. 18 - Prob. 1QCh. 18 - Prob. 2QCh. 18 - Prob. 3QCh. 18 - Prob. 4QCh. 18 - Prob. 5QCh. 18 - Prob. 1RQCh. 18 - Prob. 2RQCh. 18 - Prob. 3RQCh. 18 - Prob. 4RQCh. 18 - Prob. 5RQ
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