Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 18, Problem 2RQ
Summary Introduction

To review:

Definition of the following terminologies:

1) Processivity

2) Replisome

3) Exonuclease

4) DNA ligase

5) Replication fork

Introduction:

Deoxyribonucleic acid (DNA) replication is a complex process that involves a number of enzymes and proteins, which act together to form copies of the parent DNA strands. During replication, enzymes like DNA polymerase, primase, DNA ligase, exonuclease, helicase, topoisomerase, and many more help in various complex stages of replication. Here, some of the features of enzymes including their roles are discussed.

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QUESTION 25 During lagging strand synthesis of DNA, the RNA primers are replaced with DNA by __________.       DNA Polymerase I     DNA Polymerase II     DNA Polymerase III     Primase
Question Number 3: Write the sequence of the mRNA molecule synthesized from a DNA template coding strand having the sequence 5’ – ATCGTACCGTTA – 3
QUESTION NO. 1 Base excision repair A. is used only for bases that have been deaminated. B. uses enzymes called DNA glycosylases to generate an abasic sugar site. C. removes about 10 to 15 nucleotides. D. does not require an endonuclease. E. recognizes a bulky lesion. QUESTION NO. 2  Termination of a prokaryotic transcriptA. is a random process. B. requires the presence of the rho subunit of the holoenzyme. C. does not require rho factor if the end of the gene contains a G-C rich palindrome. D. is most efficient if there is an A-T-rich segment at the end of the gene. E. requires an ATPase in addition to rho factor.   QUESTION NO. 3  Eukaryotic transcription A. is independent of the presence of upstream consensus sequences. B. may involve a promoter located within the region transcribed rather than upstream. C. requires a separate promoter region for each of the three ribosomal RNAs transcribed. D. requires that…

Chapter 18 Solutions

Biochemistry: The Molecular Basis of Life

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