Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 9, Problem 10QP

The pre-mRNA transcript and protein made by several mutant genes were examined. The results are given below. Determine where in the gene a likely mutation lies: the promoter region, exon, intron, cap on mRNA, or ribosome binding site.

  1. a. normal-length transcript, normal-length nonfunctional protein
  2. b. normal-length transcript, no protein made
  3. c. normal-length transcript, normal-length mRNA, short nonfunctional protein
  4. d. normal-length transcript, longer mRNA, shorter nonfunctional protein
  5. e. transcript never made
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a) What is a gene promoter? b) What proteins bind to a promoter? c) What do those proteins do to control gene expression?
Consider the following mRNA base sequence 5' CUG-CAC 3' (a) What dipeptide is coded for by this mRNA? (b) What dipeptide is formed if a mutation converts CUG to CUU? (c) What dipeptide is formed if a mutation converts CAC to CGC? (d) What dipeptide is formed if a mutation converts CUG to CUU and CAC to CGC?
a)  introns removed   b)  exons removed   c)  5' cap added   d)  3' cap added   e)  poly G tail added to 5' end   f)  poly A tail added to 3' end   g)  a cap binding protein added to the 5' end   h)  poly A binding proteins added   i)  of these answers, b, c, and f only   j)  of these answers, a, c, and f only . k)  of these answers a, c, f, g, and h only Pre-mRNA must undergo which of the following modifications before leaving the nucleus?

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Human Heredity: Principles and Issues (MindTap Course List)

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