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You are an expert witness called by the defense in a case in which a former employee is suing an industrial company because his son was born with muscular dystrophy, an X-linked recessive disorder. The employee claims that he was exposed to mutagenic chemicals in the workplace that caused his son’s illness. His attorney argues that neither the employee nor his wife or their parents have this genetic disorder, and, therefore, the disease in the employee’s son represents a new mutation. How would you analyze this case? What would you say to the jury to refute this man’s case?

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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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Section
BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 11, Problem 7QP
Textbook Problem
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You are an expert witness called by the defense in a case in which a former employee is suing an industrial company because his son was born with muscular dystrophy, an X-linked recessive disorder. The employee claims that he was exposed to mutagenic chemicals in the workplace that caused his son’s illness. His attorney argues that neither the employee nor his wife or their parents have this genetic disorder, and, therefore, the disease in the employee’s son represents a new mutation. How would you analyze this case? What would you say to the jury to refute this man’s case?

Summary Introduction

To explain: The reason why X-linked recessive allele of muscular dystrophy may be present in the family of the employee which affected his son.

Introduction: X-linked recessive alleles are expressed in homozygous individuals. Mother can be a carrier of the mutated X-linked recessive allele because she is heterozygous for the condition and did not develop any diseased condition.

Explanation of Solution

Muscular dystrophy is an X-linked recessive disorder, which is expressed only when it is present in homozygous condition. The employee claims that he and his wife do not suffer from a genetic disorder, but they can be a carrier of the mutated gene. As the son of the employee is affected by the condition; so, he must be having X-linked recessive allele, which he got from his mother...

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