To discuss:
The CO2 loading in the systemic tissues that influences the unloading of O2; the meaning of the utilization coefficient, and the normal resting value.
Introduction:
The respiratory involves in the exchange of gases such as oxygen (O2) to the tissues in the body and to remove carbon dioxide (CO2) from the tissues. Oxygen is taken up by inhalation, which reaches the systemic tissues for
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Chapter 22 Solutions
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- in respiration, T or F and explain why: The greater the solubility coefficient of a gas, the greater is the partial pressure gradient required to dissolve the gas in the fluid.arrow_forwardTrue/False – If the PO2 in the systemic capillaries is 100mmHg, and the PO2 in the tissues is 40mmHg, then O2 will diffuse from the systemic capillaries into the tissues.arrow_forwardAtelectasis effect on the oxygen hemoglobin curvearrow_forward
- Resting O2 consumption is about 250 ml/min. Resting CO2 consumption is about 200 ml/min. Both these volumes refer to volumes at STPD. How much mass is lost per day through the lungs exclusive of water loss, due to resting metabolism?arrow_forwardA forearm skeletal muscle has a hemoglobin concentration of 92 microM. An arterial occlusion of the upper arm determines a decrease in saturation at a rate of 15% per minute, and no change in blood volume. Find the muscle oxygen consumption in units of micromolo2/(100 mltissue-min).arrow_forwardThe erythrocytesedimentation rate (heaviness) testis oftenused for a blood sample as a diagnosis of immune disorders of the body andsome other diseases. Assuming that the redbloodcells are about a sphere of diameter (5 um) and density(g/ml1.125) and the density andviscosity of the plasma in which the redbloodcells are settled (Pa.s), (1025 kg/m3 10-3x1.5) respectively The acceleration m/s29.81 Calculate therate of sedimentation (settling speed) of red bloodcells. 90x 10-6m/min O 9x10-6 m/s Oarrow_forward
- Which of the folloqing statements about BPG and its effect on oxygen transport is NOT true?   BPG binds more tightly to adult Hb than fetal Hb, thus facilitating the O2 transfer to the fetus.   An initial reponse in adapting to higher altitude is increased BPG synthesis in erythrocites. This increase in BPG concentraton will shift the Hb saturation curve to a higher affinity position relative to its sea-level position, facilitating better O2 aborption and transport at higher altitudes.   The presence of BPG in mammalian erythrocytes decreases Hb affinity for O2    BPG binds Hb in its central cavity in the R-state but not in the T-state, and in this way decreasing Hb affinity for O2   BPG binds Hb in its central cavity in the T-state but not in the R-state, and in this way decreasing Hb affinity for O2arrow_forwardThe so-called PCO2 respiratory drive breaking point during a dive is about55 mm Hg. is True or False and explainarrow_forwardwhich of adult haemoglobin or foetal haemoglobin will have a lower P50 value for binding O2.  Be sure to define the term P50 and mention at a molecular level what interactions and structure differences are contribute to the observed values.arrow_forward
- Discuss the importance of the CO2/HCO3 - equilibrium in blood and in urinearrow_forwardMEASURING CO2 PRODUCTION IN ANIMALSÂ (Effect of Temperature & Effect of Size) Â make a introduction and importance to physiology. please include citation.arrow_forwardIn terms of acid/base balance, carbon dioxide represents an in the bodyObstructive respiratory pathologies result inof CO2 and would most likely cause a respiratoryarrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
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