Mestranol is synthesized by the reaction of a ketone with sodium acetylide in the presence of dilute acids. The structure of the ketone needed to prepare it is to be given. Concept introduction: When ketones are treated with sodium acetylide in the presence of dilute acids addition reaction occurs. The actylide ion adds to the carbonyl carbon and H adds to the carbonyl oxygen to yield an ynol in which the alcohol group is adjacent to a carbon in triple bond. To state: The structure of the ketone needed to prepare mestranol by reaction with sodium acetylide in the presence of dilute acids.

Question

The acid dissociation constant (Ka) for loss of a proton from cyclohexanol is 1 X10-16. a. Draw a reaction coordinate diagram for loss of a proton from cyclohexanol.

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 9.SE, Problem 51AP

Interpretation Introduction

Interpretation:

Mestranol is synthesized by the reaction of a ketone with sodium acetylide in the presence of dilute acids. The structure of the ketone needed to prepare it is to be given.

Concept introduction:

When ketones are treated with sodium acetylide in the presence of dilute acids addition reaction occurs. The actylide ion adds to the carbonyl carbon and H adds to the carbonyl oxygen to yield an ynol in which the alcohol group is adjacent to a carbon in triple bond.

To state:

The structure of the ketone needed to prepare mestranol by reaction with sodium acetylide in the presence of dilute acids.

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The acid dissociation constant (Ka) for loss of a proton from cyclohexanol is 1 X10-16. a. Draw a reaction coordinate diagram for loss of a proton from cyclohexanol.

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Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 9.SE, Problem 51AP

Interpretation Introduction

Interpretation:

Mestranol is synthesized by the reaction of a ketone with sodium acetylide in the presence of dilute acids. The structure of the ketone needed to prepare it is to be given.

Concept introduction:

When ketones are treated with sodium acetylide in the presence of dilute acids addition reaction occurs. The actylide ion adds to the carbonyl carbon and H adds to the carbonyl oxygen to yield an ynol in which the alcohol group is adjacent to a carbon in triple bond.

To state:

The structure of the ketone needed to prepare mestranol by reaction with sodium acetylide in the presence of dilute acids.

Expert Solution & Answer

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See solution

Check out sample textbook solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 9.SE, Problem 51AP

Interpretation Introduction

Interpretation:

Mestranol is synthesized by the reaction of a ketone with sodium acetylide in the presence of dilute acids. The structure of the ketone needed to prepare it is to be given.

Concept introduction:

When ketones are treated with sodium acetylide in the presence of dilute acids addition reaction occurs. The actylide ion adds to the carbonyl carbon and H adds to the carbonyl oxygen to yield an ynol in which the alcohol group is adjacent to a carbon in triple bond.

To state:

The structure of the ketone needed to prepare mestranol by reaction with sodium acetylide in the presence of dilute acids.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 9.SE, Problem 51AP

Interpretation Introduction