Concept explainers
Interpretation:
Whether the amino acid glycine will migrate toward anode or cathode in an electrophoresis is to be explained.
Concept introduction:
Isoelectric point (pI) or isoelectric pH is the pH at which the substance has zero charge. An amino acid’s pI is the average of its two pKa values.
If the pH of the solution is higher than the pI, the substance will deprotonate carrying negative charge. Conversely, if the pH is lower than the pI, the substance will be protonated and will carry a positive charge.
Any ion that has net positive charge (cations) will migrate toward the negatively charged terminal i.e. cathode, and the ion with negative charge (anions) will migrate toward positively charged terminal i.e. anode.
Want to see the full answer?
Check out a sample textbook solutionChapter 6 Solutions
ORGANIC CHEMISTRY E-BOOK W/SMARTWORK5
- Please provide the solution to the following question using Robinson annulationarrow_forwardShow the movement of electrons of the following reactionarrow_forwardComplete the mechanism for the hydrolysis shown by adding any missing bonds, charges, nonbonding electrons, and curved arrows.arrow_forward
- Please help would and explain problemarrow_forwardExplain why the alkyl halide shown here reacts much more rapidly with guanine than does a primary alkyl halide (such as pentyl chloride). The alkyl halide can react with two guanines, each in a different DNA chain, thereby cross-linking the chains. Propose a mechanism for the cross-linking reaction.arrow_forwardNucleophilic attack may appear to occur in two steps as shown below. The alcohol is the nucleophile in this example. It attacks a carbon with a δ+ charge. The second arrow shows the flow of negative charge. WHY is it necessary? The second arrow could be thought of as a resonance arrow. HOW?arrow_forward
- a. Explain why the alkyl halide shown here reacts much more rapidly with guanine than does a primary alkyl halide (such as pentyl chloride). b. The alkyl halide can react with two guanines, each in a different DNA chain, thereby cross-linking the chains. Propose a mechanism for thecross- linking reaction.arrow_forwardShow how to convert toluene to 3-hydroxybenzoic acid using the same set of reactions as in diagram but changing the order in which two or more of the steps are carried outarrow_forwardWhich substrate would undergo nucleophilic aromatic substitution the fastest with MaOMe in MeOH. The correct answer is B, but I don't know why please explain:)arrow_forward
- In the following enantioselective reaction find the product. A positive non-linear effect (NOE) was observed, Explain with reaction pathway.arrow_forwardExplain very detailed why the nitro group add to the ortho of the methyl and not to the Tbutyl group. Please use electron donating and withdrawing groups in the explanation as well as electron density.arrow_forwardDraw the structure(s) of the major organic product(s) of the following reaction. Please provide the right answer. Last attempt!!!arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning