Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 8, Problem 7TY
The EGF receptor functions as
- a receptor tyrosine kinase.
- a G-protein-coupled receptor.
- a ligand-gated ion channel.
- a transcription factor.
- none of the above.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
After it has been activated a G-protein _______.
moves along the inside of the cell's membrane and activates enzymes
binds to its receptor in the cell's nucleus and initiates translation
travels in the bloodstream to its target cell and then binds to its receptor
binds to a receptor on a nearby cell and then activates multiple proteins
A drug binds to a receptor and causes an immediate change in the electrical signaling or excitability of that cell, without activating another signaling molecule. What type of receptor is this drug most likely binding to?
G-protein coupled receptor (GPCR)
Ligand-gated ion channel
Enzyme-coupled receptor
Intracellular receptor
Voltage-gated ion channel
For a signal to be sent down an axon of a nerve cell, an action potential must be generated. This is done by..
Select one:
a. G-protein coupled receptors bind ligand, a phosphorylation cascade occurs, this causes a change in charge of the membrane due to the addition of phosphates allowing Na+ channels to open.
b. Ligand-gated K+ channels open, allowing K+ to rush out of the cell and depolarize that part of the membrane. This change in charge opens neighboring voltage-gated channels.
c. Ligand-gated Na+ channels open, allowing Na+ to rush in. This then depolarizes that region of the membrane resulting in opening neighboring voltage-gated channels.
d. Receptor tyrosine kinases have two Na+ molecules bind, this opens voltage-gated channels allowing the “signal” to pass down the axon.
Chapter 8 Solutions
Principles of Biology
Ch. 8.1 - What is the signaling molecule in this example?Ch. 8.1 - Prob. 2CCCh. 8.1 - Prob. 3CCCh. 8.1 - A general reason for cell signaling is to respond...Ch. 8.1 - Prob. 2TYKCh. 8.1 - Prob. 3TYKCh. 8.2 - Prob. 1BCCh. 8.2 - Prob. 1TYKCh. 8.2 - Prob. 2TYKCh. 8.3 - Prob. 1CC
Ch. 8.3 - What has to happen for the a and subunits of the...Ch. 8.3 - Prob. 1TYKCh. 8.3 - After a G-protein-coupled receptor is activated,...Ch. 8.4 - Prob. 1TYKCh. 8.5 - Look ahead to Figures 13.9 and, in particular,...Ch. 8.5 - Prob. 1TYKCh. 8.5 - Prob. 2TYKCh. 8.6 - Prob. 1CCCh. 8.6 - Prob. 2CCCh. 8.6 - Prob. 3CCCh. 8.6 - Prob. 1TYKCh. 8.6 - Prob. 2TYKCh. 8 - Prob. 1TYCh. 8 - Prob. 2TYCh. 8 - Prob. 3TYCh. 8 - Prob. 4TYCh. 8 - Which of the following is not an example of a cell...Ch. 8 - Prob. 6TYCh. 8 - The EGF receptor functions as a receptor tyrosine...Ch. 8 - Prob. 8TYCh. 8 - Prob. 9TYCh. 8 - The benefit of second messengers in signal...Ch. 8 - Prob. 1CCQCh. 8 - Prob. 2CCQCh. 8 - Prob. 3CCQCh. 8 - Discuss and compare several different types of...Ch. 8 - Prob. 2CBQ
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which of the following is an example of heterodimeric protein?a) Integrinb) Antibodiesc) Receptor tyrosine kinased) G-protein coupled receptorarrow_forwardWhich receptor undergoes clustering and autophosphorylation in response to activation by a signal? Group of answer choices: a)Ligand-gated ion channels b)Receptor Tyrosine Kinases (RTKs) c)G-Protein Coupled Receptors (GPCRs) d)Nuclear Receptorsarrow_forwardWhich of these is NOT a response that occurs when an intercellular chemical signal binds to a membrane-bound receptor? 1. Enzymes at the inner surface of the cell are directly activated. 2. Ion channels open or close. 3. Enzymes add phosphate groups to certain proteins in the cell. 4. The chemical signal and receptor bind to DNA in the nucleus. 5. Activated G proteins activate enzymes that produce intracellular messengers.arrow_forward
- Which of the following statements most accurately describes what happens when an antagonist binds to a receptor? The antagonist binds non-covalently to the receptor and promotes internalisation of the receptor. Antagonist binding alters the structure of the receptor making it unable to function normally. At sufficiently high concentrations the antagonist can prevent the receptor from binding to its natural (endogenous) ligand. The antagonist-receptor complex binds to a heterotrimeric G protein forming a stable and inactive ternary complex.arrow_forwardAn extracellular signaling molecule binds to cell surface receptor. This cell surface receptor changes shape and activates a trimeric G-protein. What kind of receptor is this? a) Ion-channel coupled receptor b) Receptor Tyrosine Kinase c) G-Protein coupled receptor d) All of the other answers are correct e) Enzyme-coupled receptorarrow_forwardExcept for?, all of the following signals may trigger receptor conformational changes without reaching the plasma membrane. o a. Receptors for steroid hormones. Tyrosine kinase receptors are a kind of receptor that binds to tyrosine phosphatase. Voltage-gated ion channels (OC). G protein-coupled receptors (GPCRs).arrow_forward
- How can molecules pass through a closed gate such as in ligand-gated channel protein? Group of answer choices Receptor must receive pressure to open the gate. Receptor must receive electrical signals to open the gate. Receptor must receive signals or stimulus from the neurotransmitter to open the gate. The ligand-gated channel protein is always open, and it does need any stimulusarrow_forwardCompound C is a pharmaceutical agent that blocks AMPK activity. How might compound C influence adaptation following resistance exercise? How might compound C influence adaptation following endurance exercise? Be specific and remember this section is Molecular Signalingarrow_forwardWhich of the following best describes the type of receptor a beta-antagonist drugs acts on a.Ligand-regulated transmembrane enzymes b.Ion channel c.G protein-coupled receptor d.Intracellular lipid-soluble signalingarrow_forward
- Which of the following ion channels are always sensitive to small changes in electric charge? stress-activated channels ligand-gated channels with extracellular ligands voltage-gated channels ligand-gated channels with intracellular ligands all of the abovearrow_forwardwhat characteristic is not one attributed to a second messenger? a. Intracellular signaling molecule b. molecules that can easily pass across membrane bilayers. c. molecules that can act as allosteric effectors for signaling proteins. d. molecules that can be rapidly converted between active and inactive forms. e. molecules that are synthesized in response to receptor/signal interaction.arrow_forwardWhen a signal molecule (hormone) binds at a G protein-coupled receptor, the G protein a. Binds with GTP b. Becomes deactivated c. Binds with cAMP d. Binds with a kinase e. Binds to the signal moleculearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license